Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells
Cluster of differentiation 1c (CD1c)-dependent self-reactive T cells are abundant in human blood, but self-antigens presented by CD1c to the T-cell receptors of these cells are poorly understood. Here we present a crystal structure of CD1c determined at 2.4 Å revealing an extended ligand binding po...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
2016-03-01.
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Subjects: | |
Online Access: | Get fulltext Get fulltext |