Hippocampal amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid GluA1 (AMPA GluA1) receptor subunit involves in learning and memory improvement following treatment with Centella asiatica extract in adolescent rats

Introduction: Centella asiatica is an herbal plant that contains phytochemicals that are widely believed to have positive effects on cognitive function. The adolescent stage is a critical development period for the maturation of brain processes that encompass changes in physical and psychological sy...

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Main Authors: Abdullah, JM (Author), Adenan, MI (Author), Jaafar, H (Author), Mohamad, H (Author), Mohammed, FR (Author), Muhammad, TST (Author), Muthuraju, S (Author), Senik, MH (Author), Wong, JH (Author), Yeo, NABMY (Author), Yusof, SR (Author), Zhang, JL (Author)
Format: Article
Language:English
Published: 2018
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Summary:Introduction: Centella asiatica is an herbal plant that contains phytochemicals that are widely believed to have positive effects on cognitive function. The adolescent stage is a critical development period for the maturation of brain processes that encompass changes in physical and psychological systems. However, the effect of C.asiatica has not been extensively studied in adolescents. The aim of this study was therefore to investigate the effects of a C.asiatica extract on the enhancement of learning and memory in adolescent rats.
DOI:10.1002/brb3.1093