Effects of proton pump inhibitor on the human gut microbiome profile in multi-ethnic groups in Singapore
INTRODUCTION The objectives of this study were to examine the effects of ethnicity, gender and a proton pump inhibitor (PPI), omeprazole, on the human gut microbiome. PPIs are commonly used for the treatment of acid-related disorders. We hypothesised that PPI therapy might perturb microbial communit...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2019
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |
| LEADER | 01492nam a2200397Ia 4500 | ||
|---|---|---|---|
| 001 | 10.11622-smedj.2018152 | ||
| 008 | 220223s2019 CNT 000 0 und d | ||
| 245 | 1 | 0 | |a Effects of proton pump inhibitor on the human gut microbiome profile in multi-ethnic groups in Singapore |
| 260 | 0 | |c 2019 | |
| 650 | 0 | 4 | |a AGE |
| 650 | 0 | 4 | |a ALTER |
| 650 | 0 | 4 | |a BACTERIA |
| 650 | 0 | 4 | |a BUTYRATE |
| 650 | 0 | 4 | |a CLOSTRIDIUM-DIFFICILE INFECTION |
| 650 | 0 | 4 | |a DIARRHEA |
| 650 | 0 | 4 | |a DIVERSITY |
| 650 | 0 | 4 | |a gastroesophageal reflux disease |
| 650 | 0 | 4 | |a gastrointestinal microbiome |
| 650 | 0 | 4 | |a omeprazole |
| 650 | 0 | 4 | |a RISK |
| 856 | |z View Fulltext in Publisher |u https://doi.org/10.11622/smedj.2018152 | ||
| 520 | 3 | |a INTRODUCTION The objectives of this study were to examine the effects of ethnicity, gender and a proton pump inhibitor (PPI), omeprazole, on the human gut microbiome. PPIs are commonly used for the treatment of acid-related disorders. We hypothesised that PPI therapy might perturb microbial communities and alter the gut microbiome. | |
| 700 | 1 | 0 | |a Aazmi, S |e author |
| 700 | 1 | 0 | |a Ang, DSW |e author |
| 700 | 1 | 0 | |a Ang, TL |e author |
| 700 | 1 | 0 | |a Deng, J |e author |
| 700 | 1 | 0 | |a Hsiang, JC |e author |
| 700 | 1 | 0 | |a Koo, SH |e author |
| 700 | 1 | 0 | |a Lee, EJD |e author |
| 700 | 1 | 0 | |a Lee, LS |e author |
| 700 | 1 | 0 | |a Mohamed, EHM |e author |
| 700 | 1 | 0 | |a Salleh, MZ |e author |
| 700 | 1 | 0 | |a Teh, LK |e author |
| 700 | 1 | 0 | |a Yang, H |e author |
| 700 | 1 | 0 | |a Yap, SY |e author |
| 773 | |t SINGAPORE MEDICAL JOURNAL | ||