An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils

by Emil Dandanell Agerschou, Patrick Flagmeier, Theodora Saridaki, Céline Galvagnion, Daniel Komnig, Laetitia Heid, Vibha Prasad, Hamed Shaykhalishahi, Dieter Willbold, Christopher M Dobson, Aaron Voigt, Bjoern Falkenburger, Wolfgang Hoyer, Alexander K Buell
Published 2019-08-01

Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy

by Christine Röder, Nicola Vettore, Lena N. Mangels, Lothar Gremer, Raimond B. G. Ravelli, Dieter Willbold, Wolfgang Hoyer, Alexander K. Buell, Gunnar F. Schröder
Published 2019-08-01

Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation

by Thibault Viennet, Michael M. Wördehoff, Boran Uluca, Chetan Poojari, Hamed Shaykhalishahi, Dieter Willbold, Birgit Strodel, Henrike Heise, Alexander K. Buell, Wolfgang Hoyer, Manuel Etzkorn
Published 2018-05-01

Structural Insights into Curli CsgA Cross-β Fibril Architecture Inspire Repurposing of Anti-amyloid Compounds as Anti-biofilm Agents.

by Sergei Perov, Ofir Lidor, Nir Salinas, Nimrod Golan, Einav Tayeb-Fligelman, Maya Deshmukh, Dieter Willbold, Meytal Landau
Published 2019-08-01

Amyloid β Oligomeric Species Present in the Lag Phase of Amyloid Formation.

by Martin Wolff, Dmitry Unuchek, Bo Zhang, Valentin Gordeliy, Dieter Willbold, Luitgard Nagel-Steger
Published 2015-01-01

Molecular interactions between prions as seeds and recombinant prion proteins as substrates resemble the biological interspecies barrier in vitro.

by Giannantonio Panza, Lars Luers, Jan Stöhr, Luitgard Nagel-Steger, Jürgen Weiss, Detlev Riesner, Dieter Willbold, Eva Birkmann
Published 2010-12-01