Aged 2 Article 2 Case-Control Studies 2 Female Humans 2 Male 2 Middle Aged 2 RNA, Long Noncoding 2 Severity of Illness Index 2 adult 2 aged 2 blood 2 case control study 2 controlled study 2 cytokine 2 disease severity 2 female 2 gene expression 2 genetics 2 human 2 intercellular adhesion molecule 1 2 interleukin 17 2 interleukin 6 2 long untranslated RNA 2 major clinical study 2 male 2 middle aged 2 mortality 2 severity of illness index 2 APACHE 1