Showing 1 - 12 results of 12 for search '"Caenorhabditis elegans"', query time: 0.33s Refine Results
  1. 1
    Gene pathways that delay Caenorhabditis elegans reproductive senescence.
    “... RNA interference (RNAi) screen, we identified 32 Caenorhabditis elegans gene inactivations that delay...”
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  2. 2
    Genetic regulation of Caenorhabditis elegans lysosome related organelle function.
    “... are associated with human immune disorders and neurological disease. Caenorhabditis elegans LROs are the site...”
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    Article
  3. 3
    PIWI associated siRNAs and piRNAs specifically require the Caenorhabditis elegans HEN1 ortholog henn-1.
    “... for endogenous siRNA formation and activity in Caenorhabditis elegans, we developed a GFP-based sensor...”
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  4. 4
    Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response.
    by Kai Mao, Peter Breen, Gary Ruvkun
    Published 2020-12-01
    “... (MDA5) mediate antiviral responses. Here, we report that mitochondrial dysfunction in Caenorhabditis...”
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  5. 5
    Lifespan regulation by evolutionarily conserved genes essential for viability.
    by Sean P Curran, Gary Ruvkun
    Published 2007-04-01
    “... 2,700 genes essential for Caenorhabditis elegans development and identified 64 genes that extend...”
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    Article
  6. 6
    Two membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signaling.
    by Patrick J Hu, Jinling Xu, Gary Ruvkun
    Published 2006-07-01
    “... and metabolism. In humans, Akt/PKB is dysregulated in diabetes and cancer; in Caenorhabditis elegans, Akt/PKB...”
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  7. 7
    Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways.
    by David E Shore, Christopher E Carr, Gary Ruvkun
    Published 2012-01-01
    “... of cytoprotective pathways upregulated by 160 gene inactivations known to increase Caenorhabditis elegans longevity...”
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    Article
  8. 8
    Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1
    by Nicolas J Lehrbach, Gary Ruvkun
    Published 2016-08-01
    “... attacks or proteasome inhibitor drugs. In Caenorhabditis elegans, this response requires SKN-1, a...”
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    Article
  9. 9
    Dual regulation of the lin-14 target mRNA by the lin-4 miRNA.
    by Zhen Shi, Gabriel Hayes, Gary Ruvkun
    Published 2013-01-01
    “... modest translational repression and more significant mRNA destabilization. In Caenorhabditis elegans...”
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    Article
  10. 10
    Repression of germline RNAi pathways in somatic cells by retinoblastoma pathway chromatin complexes.
    by Xiaoyun Wu, Zhen Shi, Mingxue Cui, Min Han, Gary Ruvkun
    Published 2012-01-01
    “... of species to suppress cell proliferation. The Caenorhabditis elegans retinoblastoma gene and many...”
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    Article
  11. 11
    Genomic and Functional Characterization of Enterococcus faecalis Isolates Recovered From the International Space Station and Their Potential for Pathogenicity
    “... humidity. Finally, pathogenicity of the ISS strains was evaluated in the model organism Caenorhabditis...”
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  12. 12
    The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications.
    “... eri-6/7 was identified in the nematode Caenorhabditis elegans by the enhanced response to exogenous...”
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