Causal inference for heritable phenotypic risk factors using heterogeneous genetic instruments.

by Jingshu Wang, Qingyuan Zhao, Jack Bowden, Gibran Hemani, George Davey Smith, Dylan S Small, Nancy R Zhang
Published 2021-06-01

The MR-Base platform supports systematic causal inference across the human phenome

by Gibran Hemani, Jie Zheng, Benjamin Elsworth, Kaitlin H Wade, Valeriia Haberland, Denis Baird, Charles Laurin, Stephen Burgess, Jack Bowden, Ryan Langdon, Vanessa Y Tan, James Yarmolinsky, Hashem A Shihab, Nicholas J Timpson, David M Evans, Caroline Relton, Richard M Martin, George Davey Smith, Tom R Gaunt, Philip C Haycock
Published 2018-05-01

An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome

by Tom G Richardson, Sean Harrison, Gibran Hemani, George Davey Smith
Published 2019-03-01

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

by Tom G. Richardson, Gibran Hemani, Tom R. Gaunt, Caroline L. Relton, George Davey Smith
Published 2020-01-01

Orienting the causal relationship between imprecisely measured traits using GWAS summary data.

by Gibran Hemani, Kate Tilling, George Davey Smith
Published 2017-11-01

Using the MR-Base platform to investigate risk factors and drug targets for thousands of phenotypes [version 1; peer review: 2 approved]

by Venexia M Walker, Neil M Davies, Gibran Hemani, Jie Zheng, Philip C Haycock, Tom R Gaunt, George Davey Smith, Richard M Martin
Published 2019-07-01