Search Results - "somatic mutation"

1

High-throughput mutation profiling identifies frequent somatic mutations in advanced gastric adenocarcinoma.

by Jeeyun Lee, Paul van Hummelen, Christina Go, Emanuele Palescandolo, Jiryeon Jang, Ha Young Park, So Young Kang, Joon Oh Park, Won Ki Kang, Laura MacConaill, Kyoung-Mee Kim
Published 2012-01-01

“...%), and CDKN2A (0.8%). Six samples harbored concomitant somatic mutations. Mutations of CTNNB1 were...”

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2

Comprehensive molecular characterization of gastric cancer patients from phase II second-line ramucirumab plus paclitaxel therapy trial

by Seung Tae Kim, Jason K. Sa, Sung Yong Oh, Kyung Kim, Jung Yong Hong, Won Ki Kang, Kyoung-Mee Kim, Jeeyun Lee
Published 2021-01-01

“... molecular determinants, including EBV status, and somatic mutation in GNAQ to ramucirumab activity...”

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3

Molecular Characterization of Urothelial Carcinoma of the Bladder and Upper Urinary Tract

by Ji Yun Lee, Kyung Kim, Hyun Hwan Sung, Hwang Gyun Jeon, Byong Chang Jeong, Seong Il Seo, Seong Soo Jeon, Hyun Moo Lee, Han-Yong Choi, Ghee-Young Kwon, Kyoung-Mee Kim, Jeeyun Lee, Ho Yeong Lim, Se Hoon Park
Published 2018-02-01

“... samples: single nucleotide variants were the most common type of somatic mutation (479/508, 94.3...”

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4

Unforeseen clonal evolution of tumor cell population in recurrent and metastatic dermatofibrosarcoma protuberans.

by Ensel Oh, Hae Min Jeong, Mi Jeong Kwon, Sang Yun Ha, Hyung Kyu Park, Ji-Young Song, Yu Jin Kim, Jong-Sun Choi, Eun Hee Lee, Jeeyun Lee, Yoon-La Choi, Young Kee Shin
Published 2017-01-01

“... various genomic alterations, namely somatic mutations, copy number variations, and chromosomal...”

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5

High-throughput genotyping in metastatic esophageal squamous cell carcinoma identifies phosphoinositide-3-kinase and BRAF mutations.

by Chi Hoon Maeng, Jeeyun Lee, Paul van Hummelen, Se Hoon Park, Emanuele Palescandolo, Jiryeon Jang, Ha Young Park, So Young Kang, Laura MacConaill, Kyoung-Mee Kim, Young-Mog Shim
Published 2012-01-01

“... screened for the presence of somatic mutations using OncoMap platform with the aim of defining subsets...”

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6

Genetic aberrations in imatinib-resistant dermatofibrosarcoma protuberans revealed by whole genome sequencing.

by Jung Yong Hong, Xiao Liu, Mao Mao, Miao Li, Dong Il Choi, Shin Woo Kang, Jeeyun Lee, Yoon La Choi
Published 2013-01-01

“... identified newly emerged 8 non-synonymous somatic mutations of the genes (ACAP2, CARD10, KIAA0556, PAAQR7...”

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7

High-throughput sequencing and copy number variation detection using formalin fixed embedded tissue in metastatic gastric cancer.

by Seokhwi Kim, Jeeyun Lee, Min Eui Hong, In-Gu Do, So Young Kang, Sang Yun Ha, Seung Tae Kim, Se Hoon Park, Won Ki Kang, Min-Gew Choi, Jun Ho Lee, Tae Sung Sohn, Jae Moon Bae, Sung Kim, Duk-Hwan Kim, Kyoung-Mee Kim
Published 2014-01-01

“... and immunohistochemistry. Frequently detected somatic mutations included TP53 (28.17%), APC (10.1%), PIK3CA (5.6%), KRAS...”

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8

Systematic Evaluation of Gastric Tumor Cell Index and Two-Drug Combination Therapy via 3-Dimensional High-Throughput Drug Screening

by Sung Hee Lim, Sung Hee Lim, Jason K. Sa, Dong Woo Lee, Jusun Kim, Seung Tae Kim, Se Hoon Park, Bosung Ku, Joon Oh Park, Young Suk Park, Hoyeong Lim, Won Ki Kang, Do-Hyun Nam, Do-Hyun Nam, Jeeyun Lee
Published 2019-11-01

“... sensitive to HER2 and PARP inhibition therapy. Finally, somatic mutations in TP53 and CDKN2A with MYC...”

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