Search Results - "Hit to lead"

1

Process of Fragment-Based Lead Discovery—A Perspective from NMR

by Rongsheng Ma, Pengchao Wang, Jihui Wu, Ke Ruan
Published 2016-07-01
“... structure model generation. For weak binders, the initial hit-to-lead evolution can be guided by structural...”

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2

NMR Fragment-Based Screening against Tandem RNA Recognition Motifs of TDP-43

by Gilbert Nshogoza, Yaqian Liu, Jia Gao, Mingqing Liu, Sayed Ala Moududee, Rongsheng Ma, Fudong Li, Jiahai Zhang, Jihui Wu, Yunyu Shi, Ke Ruan
Published 2019-06-01
“... studies regarding the hit-to-lead evolution against the TDP-43 RRM domain....”

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