Temporal evolution of heme oxygenase-1 expression in reactive astrocytes and microglia in response to traumatic brain injury

by Alexander Morita, Amandine Jullienne, Arjang Salehi, Mary Hamer, Emon Javadi, Yasir Alsarraj, Jiping Tang, John H. Zhang, William J. Pearce, André Obenaus
Published 2020-03-01

Glial Cells: Role of the Immune Response in Ischemic Stroke

by Shenbin Xu, Jianan Lu, Anwen Shao, John H. Zhang, John H. Zhang, John H. Zhang, Jianmin Zhang, Jianmin Zhang, Jianmin Zhang
Published 2020-02-01

Activation of GPR40 attenuates neuroinflammation and improves neurological function via PAK4/CREB/KDM6B pathway in an experimental GMH rat model

by Jie Xiao, Tao Cai, Yuanjian Fang, Rui Liu, Jerry J. Flores, Wenna Wang, Ling Gao, Yu Liu, Qin Lu, Lihui Tang, John H. Zhang, Hongwei Lu, Jiping Tang
Published 2021-07-01

Rh-CSF1 attenuates neuroinflammation via the CSF1R/PLCG2/PKCε pathway in a rat model of neonatal HIE

by Xiao Hu, Shirong Li, Desislava Met Doycheva, Lei Huang, Cameron Lenahan, Rui Liu, Juan Huang, Shucai Xie, Jiping Tang, Gang Zuo, John H. Zhang
Published 2020-06-01

PPARγ-induced upregulation of CD36 enhances hematoma resolution and attenuates long-term neurological deficits after germinal matrix hemorrhage in neonatal rats

by Jerry J. Flores, Damon Klebe, William B. Rolland, Tim Lekic, Paul R. Krafft, John H. Zhang
Published 2016-03-01

NT-4 attenuates neuroinflammation via TrkB/PI3K/FoxO1 pathway after germinal matrix hemorrhage in neonatal rats

by Tianyi Wang, Junyi Zhang, Peng Li, Yan Ding, Jiping Tang, Gang Chen, John H. Zhang
Published 2020-05-01

Activation of melanocortin receptor 4 with RO27-3225 attenuates neuroinflammation through AMPK/JNK/p38 MAPK pathway after intracerebral hemorrhage in mice

by Shengpan Chen, Lianhua Zhao, Prativa Sherchan, Yan Ding, Jing Yu, Derek Nowrangi, Jiping Tang, Ying Xia, John H. Zhang
Published 2018-04-01

Aggf1 attenuates neuroinflammation and BBB disruption via PI3K/Akt/NF-κB pathway after subarachnoid hemorrhage in rats

by Qiquan Zhu, Budbazar Enkhjargal, Lei Huang, Tongyu Zhang, Chengmei Sun, Zhiyi Xie, Pei Wu, Jun Mo, Jiping Tang, Zongyi Xie, John H. Zhang
Published 2018-06-01

Recombinant CCL17-dependent CCR4 activation alleviates neuroinflammation and neuronal apoptosis through the PI3K/AKT/Foxo1 signaling pathway after ICH in mice

by Shuixiang Deng, Peng Jin, Prativa Sherchan, Shengpeng Liu, Yuhui Cui, Lei Huang, John H. Zhang, Ye Gong, Jiping Tang
Published 2021-03-01

TREM2 activation attenuates neuroinflammation and neuronal apoptosis via PI3K/Akt pathway after intracerebral hemorrhage in mice

by Shengpan Chen, Jianhua Peng, Prativa Sherchan, Yongjie Ma, Sishi Xiang, Feng Yan, Hao Zhao, Yong Jiang, Ning Wang, John H. Zhang, Hongqi Zhang
Published 2020-05-01

Activation of MC1R with BMS-470539 attenuates neuroinflammation via cAMP/PKA/Nurr1 pathway after neonatal hypoxic-ischemic brain injury in rats

by Shufeng Yu, Desislava Met Doycheva, Marcin Gamdzyk, Yijun Yang, Cameron Lenahan, Gaigai Li, Dujuan Li, Lifei Lian, Jiping Tang, Jun Lu, John H. Zhang
Published 2021-01-01

Bliverdin reductase-A improves neurological function in a germinal matrix hemorrhage rat model

by Yiting Zhang, Yan Ding, Tai Lu, Yixin Zhang, Ningbo Xu, Lingyan Yu, Devin W. McBride, Jerry J. Flores, Jiping Tang, John H. Zhang
Published 2018-02-01

Ezetimibe Attenuates Oxidative Stress and Neuroinflammation via the AMPK/Nrf2/TXNIP Pathway after MCAO in Rats

by Jing Yu, Wen-na Wang, Nathanael Matei, Xue Li, Jin-wei Pang, Jun Mo, Sheng-pan Chen, Ji-ping Tang, Min Yan, John H. Zhang
Published 2020-01-01

DKK3 attenuates JNK and AP-1 induced inflammation via Kremen-1 and DVL-1 in mice following intracerebral hemorrhage

by Yang Xu, Derek Nowrangi, Hui Liang, Tian Wang, Lingyan Yu, Tai Lu, Zhengyang Lu, John H. Zhang, Benyan Luo, Jiping Tang
Published 2020-04-01

Recombinant CTRP9 administration attenuates neuroinflammation via activating adiponectin receptor 1 after intracerebral hemorrhage in mice

by Lianhua Zhao, Shengpan Chen, Prativa Sherchan, Yan Ding, Wei Zhao, Zaiyu Guo, Jing Yu, Jiping Tang, John H. Zhang
Published 2018-07-01

Activation of retinoid X receptor by bexarotene attenuates neuroinflammation via PPARγ/SIRT6/FoxO3a pathway after subarachnoid hemorrhage in rats

by Yuchun Zuo, Lei Huang, Budbazar Enkhjargal, Weilin Xu, Ocak Umut, Zachary D. Travis, Guangyu Zhang, Jiping Tang, Fei Liu, John H. Zhang
Published 2019-02-01

Activation of dopamine D1 receptor decreased NLRP3-mediated inflammation in intracerebral hemorrhage mice

by Tian Wang, Derek Nowrangi, Lingyan Yu, Tai Lu, Jiping Tang, Bing Han, Yuxin Ding, Fenghua Fu, John H. Zhang
Published 2018-01-01

Rh-relaxin-2 attenuates degranulation of mast cells by inhibiting NF-κB through PI3K-AKT/TNFAIP3 pathway in an experimental germinal matrix hemorrhage rat model

by Peng Li, Gang Zhao, Fanfan Chen, Yan Ding, Tianyi Wang, Shengpeng Liu, Weitian Lu, Weilin Xu, Jerry Flores, Umut Ocak, Tongyu Zhang, John H. Zhang, Jiping Tang
Published 2020-08-01

Orexin A alleviates neuroinflammation via OXR2/CaMKKβ/AMPK signaling pathway after ICH in mice

by Tao Li, Weilin Xu, Jinsong Ouyang, Xiaoyang Lu, Prativa Sherchan, Cameron Lenahan, Giselle Irio, John H. Zhang, Jianhua Zhao, Yongfa Zhang, Jiping Tang
Published 2020-06-01

Dimethyl fumarate confers neuroprotection by casein kinase 2 phosphorylation of Nrf2 in murine intracerebral hemorrhage

by Loretta O. Iniaghe, Paul R. Krafft, Damon W. Klebe, Eric K.I. Omogbai, John H. Zhang, Jiping Tang
Published 2015-10-01