Regenerative therapy for spinal cord injury using iPSC technology

by Narihito Nagoshi, Hideyuki Okano, Masaya Nakamura
Published 2020-10-01

MRI characterization of paranodal junction failure and related spinal cord changes in mice.

by Morito Takano, Keigo Hikishima, Kanehiro Fujiyoshi, Shinsuke Shibata, Akimasa Yasuda, Tsunehiko Konomi, Akiko Hayashi, Hiroko Baba, Koichi Honke, Yoshiaki Toyama, Hideyuki Okano, Masaya Nakamura
Published 2012-01-01

Novel Concept of Motor Functional Analysis for Spinal Cord Injury in Adult Mice

by Munehisa Shinozaki, Yuichiro Takahashi, Masahiko Mukaino, Nobuhito Saito, Yoshiaki Toyama, Hideyuki Okano, Masaya Nakamura
Published 2011-01-01

Cell therapy for spinal cord injury using induced pluripotent stem cells

by Narihito Nagoshi, Osahiko Tsuji, Masaya Nakamura, Hideyuki Okano
Published 2019-12-01

Transplantation of Neural Stem/Progenitor Cells at Different Locations in Mice with Spinal Cord Injury

by Hiroki Iwai, Satoshi Nori, Soraya Nishimura, Akimasa Yasuda, Morito Takano, Osahiko Tsuji, Kanehiro Fujiyoshi, Yoshiaki Toyama, Hideyuki Okano, Masaya Nakamura
Published 2014-11-01

Early surgical intervention may facilitate recovery of cervical spinal cord injury in DISH

by Osahiko Tsuji, Kota Suda, Masahiko Takahata, Satoko Matsumoto-Harmon, Miki Komatsu, Yusuke Menjo, Kota Watanabe, Ken Ishii, Masaya Nakamura, Morio Matsumoto, Akio Minami, Norimasa Iwasaki
Published 2019-03-01

Control of the Survival and Growth of Human Glioblastoma Grafted into the Spinal Cord of Mice by Taking Advantage of Immunorejection

by Go Itakura, Yoshiomi Kobayashi, Soraya Nishimura, Hiroki Iwai, Morito Takano, Akio Iwanami, Yoshiaki Toyama, Hideyuki Okano, Masaya Nakamura
Published 2015-07-01

The prospects of regenerative medicine combined with rehabilitative approaches for chronic spinal cord injury animal models

by Syoichi Tashiro, Masaya Nakamura, Hideyuki Okano
Published 2017-01-01

Human hepatocyte growth factor promotes functional recovery in primates after spinal cord injury.

by Kazuya Kitamura, Kanehiro Fujiyoshi, Jun-Ichi Yamane, Fumika Toyota, Keigo Hikishima, Tatsuji Nomura, Hiroshi Funakoshi, Toshikazu Nakamura, Masashi Aoki, Yoshiaki Toyama, Hideyuki Okano, Masaya Nakamura
Published 2011-01-01

Comparative Study of Methods for Administering Neural Stem/Progenitor Cells to Treat Spinal Cord Injury in Mice

by Yuichiro Takahashi, Osahiko Tsuji, Gentaro Kumagai, Chikako Miyauchi Hara, Hirotaka James Okano, Atsushi Miyawaki, Yoshiaki Toyama, Hideyuki Okano, Masaya Nakamura
Published 2011-06-01

Plasma as a Scaffold for Regeneration of Neural Precursor Cells after Transplantation into Rats with Spinal Cord Injury

by Mitsuko Takenaga Ph.D., Yuki Ohta, Yukie Tokura, Akemi Hamaguchi, Noboru Suzuki, Masaya Nakamura, Hideyuki Okano, Rie Igarashi
Published 2007-01-01

The adeno-associated virus rh10 vector is an effective gene transfer system for chronic spinal cord injury

by Yutaka Hoshino, Kenji Nishide, Narihito Nagoshi, Shinsuke Shibata, Nobuko Moritoki, Kota Kojima, Osahiko Tsuji, Morio Matsumoto, Jun Kohyama, Masaya Nakamura, Hideyuki Okano
Published 2019-07-01

Application of Hepatocyte Growth Factor for Acute Spinal Cord Injury: The Road from Basic Studies to Human Treatment

by Kazuya Kitamura, Narihito Nagoshi, Osahiko Tsuji, Morio Matsumoto, Hideyuki Okano, Masaya Nakamura
Published 2019-02-01

Mimicking the neurotrophic factor profile of embryonic spinal cord controls the differentiation potential of spinal progenitors into neuronal cells.

by Masaya Nakamura, Osahiko Tsuji, Barbara S Bregman, Yoshiaki Toyama, Hideyuki Okano
Published 2011-01-01

Cell therapy for spinal cord injury by using human iPSC-derived region-specific neural progenitor cells

by Keita Kajikawa, Kent Imaizumi, Munehisa Shinozaki, Shinsuke Shibata, Tomoko Shindo, Takahiro Kitagawa, Reo Shibata, Yasuhiro Kamata, Kota Kojima, Narihito Nagoshi, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano
Published 2020-09-01

Roles of ES cell-derived gliogenic neural stem/progenitor cells in functional recovery after spinal cord injury.

by Gentaro Kumagai, Yohei Okada, Junichi Yamane, Narihito Nagoshi, Kazuya Kitamura, Masahiko Mukaino, Osahiko Tsuji, Kanehiro Fujiyoshi, Hiroyuki Katoh, Seiji Okada, Shinsuke Shibata, Yumi Matsuzaki, Satoshi Toh, Yoshiaki Toyama, Masaya Nakamura, Hideyuki Okano
Published 2009-11-01

Enhanced Functional Recovery from Spinal Cord Injury in Aged Mice after Stem Cell Transplantation through HGF Induction

by Morito Takano, Soya Kawabata, Shinsuke Shibata, Akimasa Yasuda, Satoshi Nori, Osahiko Tsuji, Narihito Nagoshi, Akio Iwanami, Hayao Ebise, Keisuke Horiuchi, Hideyuki Okano, Masaya Nakamura
Published 2017-03-01

Treatment with a Gamma-Secretase Inhibitor Promotes Functional Recovery in Human iPSC- Derived Transplants for Chronic Spinal Cord Injury

by Toshiki Okubo, Narihito Nagoshi, Jun Kohyama, Osahiko Tsuji, Munehisa Shinozaki, Shinsuke Shibata, Yoshitaka Kase, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano
Published 2018-12-01

Pretreatment with a γ-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury

by Toshiki Okubo, Akio Iwanami, Jun Kohyama, Go Itakura, Soya Kawabata, Yuichiro Nishiyama, Keiko Sugai, Masahiro Ozaki, Tsuyoshi Iida, Kohei Matsubayashi, Morio Matsumoto, Masaya Nakamura, Hideyuki Okano
Published 2016-10-01

First-in-human clinical trial of transplantation of iPSC-derived NS/PCs in subacute complete spinal cord injury: Study protocol

by Keiko Sugai, Miho Sumida, Tomoko Shofuda, Ryo Yamaguchi, Takashi Tamura, Tsuneo Kohzuki, Takayuki Abe, Reo Shibata, Yasuhiro Kamata, Shuhei Ito, Toshiki Okubo, Osahiko Tsuji, Satoshi Nori, Narihito Nagoshi, Shinya Yamanaka, Shin Kawamata, Yonehiro Kanemura, Masaya Nakamura, Hideyuki Okano
Published 2021-12-01