Engineered Cpf1 variants with altered PAM specificities

by Schneider, Martin W, Yamano, Takashi, Nishimasu, Hiroshi, Nureki, Osamu, Crosetto, Nicola, Gao, Linyi, Cox, David Benjamin Turitz, Yan, Winston Xia, Manteiga, John Colonnese, Zhang, Feng
Published 2018

Engram Cell Excitability State Determines the Efficacy of Memory Retrieval

by Pignatelli di Spinazzola, Michele, Rivera, Tomás, Roy, Dheeraj, Lovett, Chanel W. L., Smith, Lillian, Muralidhar, Shruti, Tonegawa, Susumu
Published 2020

Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis

by Lee, Kyungheon, Song, Jun, Weissleder, Ralph, Lee, Hakho, Chen, Sidi, Sanjana, Neville E, Zheng, Kaijie, Shalem, Ophir, Shi, Xi, Scott, David Arthur, Pan, Jennifer Q., Zhang, Feng, Sharp, Phillip A.
Published 2017

Identification and Rescue of  -Synuclein Toxicity in Parkinson Patient-Derived Neurons

by Chung, Chee Yeun, Khurana, Vikram, Auluck, Pavan K., Tardiff, Daniel F., Mazzulli, Joseph R., Soldner, Frank, Baru, Valeriya, Lou, Yali, Freyzon, Yelena, Cho, Sukhee, Muffat, Julien, Mitalipova, Maisam, Pluth, Michael D., Jui, Nathan T., Schule, Birgitt, Lippard, Stephen J., Tsai, Li-Huei, Krainc, Dimitri, Jaenisch, Rudolf, Lindquist, Susan, Mungenast, Alison, Buchwald, Stephen Leffler
Published 2015

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486

by Govindarajan, Arvind, Tonegawa, Susumu, Dolan, Bridget M., Lin, Gregory G., Duron, Sergio G., Campbell, David A., Vollrath, Benedikt, Rao, B. S. Shankaranarayana, Ko, Hui-Yeon, Choi, Se-Young
Published 2013

High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage

by Slaymaker, Ian, Mesa, Pablo, Kellner, Max J., Kannan, Soumya, Brignole, Edward J, Koob, Jeremy, Feliciano, Patricia Rosa, Stella, Stefano, Abudayyeh, Omar O., Gootenberg, Jonathan S, Strecker, Jonathan, Montoya, Guillermo, Zhang, Feng
Published 2020

Nucleic acid detection with CRISPR-Cas13a/C2c2

by Lee, Jeong Wook, Essletzbichler, Patrick, Verdine, Vanessa, Donghia, Nina, Freije, Catherine A., Myhrvold, Cameron, Bhattacharyya, Roby P., Livny, Jonathan, Koonin, Eugene V., Pardis, C. Sabeti, Gootenberg, Jonathan S, Dy, Aaron James, Joung, Julia, Daringer, Nichole Marie, Regev, Aviv, Hung, Deborah T, Collins, James J., Zhang, Feng, Abudayyeh, Omar O.
Published 2017

Rapid, experience-dependent translation of neurogranin enables memory encoding

by Kuzniewska, Bozena, Pena, Franciso X., Lei, Ding J., Nguyen, Shannon, Dziembowska, Magdalena, Jones, Kendrick, Templet, Sebastian B., Zemoura, Khaled, Hwang, Hongik, Haensgen Saez, Henny M, Saenz, Christopher, Lewis, Michael C., Xu, Weifeng
Published 2019

Massively parallel single-nucleus RNA-seq with DroNc-seq

by Avraham-Davidi, Inbal, Burks, Tyler, Shekhar, Karthik, Hofree, Matan, Aguet, François, Gelfand, Ellen, Ardlie, Kristin, Weitz, David A, Rozenblatt-Rosen, Orit, Zhang, Feng, Habib, Naomi, Choudhury, Sourav, Regev, Aviv, Basu, Anindita 1978-
Published 2018

Entorhinal Cortical Ocean Cells Encode Specific Contexts and Drive Context-Specific Fear Memory

by Kitch, Lacey J, Schnitzer, Mark J, Kitamura, Takashi, Sun, Chen, Martin, Jared, Tonegawa, Susumu
Published 2017

Ventral CA1 neurons store social memory

by Itohara, Shigeyoshi, Okuyama, Teruhiro, Kitamura, Takashi, Roy, Dheeraj, Tonegawa, Susumu
Published 2017

Memory Engram Cells Have Come of Age

by Tonegawa, Susumu, Liu, Xu, Ramirez Moreno, Steve, Redondo, Roger L.
Published 2017

What is memory? The present state of the engram

by Poo, Mu-ming, Bonhoeffer, Tobias, Martin, Kelsey C., Tsien, Richard W., Fishell, Gord, Mullins, Caitlin, Gonçalves, J. Tiago, Shtrahman, Matthew, Johnston, Stephen T., Gage, Fred H., Dan, Yang, Long, John, Buzsáki, György, Stevens, Charles, Pignatelli di Spinazzola, Michele, Ryan, Tomas John, Tonegawa, Susumu, Rudenko, Andrii, Tsai, Li-Huei
Published 2017

Preplay of future place cell sequences by hippocampal cellular assemblies

by Dragoi, George, Tonegawa, Susumu
Published 2011

Engram cells retain memory under retrograde amnesia

by Ryan, Tomas John, Roy, Dheeraj, Pignatelli di Spinazzola, Michele, Arons, Autumn, Tonegawa, Susumu
Published 2017

Transmission, Development, and Plasticity of Synapses

by Littleton, J. Troy, Harris, Kathryn P.
Published 2017

Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood

by Verdine, Vanessa K., Aguet, Francois, Fulco, Charles P., Tseng, Yuen-Yi, Boehm, Jesse S., Joung, Julia, Engreitz, Jesse Michael, Konermann, Silvana M, Gootenberg, Jonathan S, Sanjana, Neville E, Wright, Jason, Yoon, Charles, Lander, Eric Steven, Zhang, Feng, Abudayyeh, Omar O.
Published 2018

Island Cells Control Temporal Association Memory

by Kitamura, Takashi, Suh, Junghyup, Kohara, Keigo, Tonegawa, Susumu, Yoshiki, Atsushi, Abe, Kuniya, Pignatelli di Spinazzola, Michele
Published 2014

Successful Execution of Working Memory Linked to Synchronized High-Frequency Gamma Oscillations

by Yamamoto, Jun, Suh, Junghyup, Takeuchi, Daigo, Tonegawa, Susumu
Published 2017

The Dendritic Branch Is the Preferred Integrative Unit for Protein Synthesis-Dependent LTP

by Govindarajan, Arvind, Israely, Inbal, Tonegawa, Susumu, Huang, Shu Ying
Published 2014