Showing 1 - 16 results of 16 for search '"IFNγ"', query time: 0.65s Refine Results
  1. 1
    Leishmania specific CD4 T cells release IFNγ that limits parasite replication in patients with visceral leishmaniasis.
    “...-inflammatory cytokines and chemokines, including IL-12, IFNγ, and TNFα, and elevated expression of IFNγ mRNA...”
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    Article
  2. 2
    Combined neutralization of interferon gamma and tumor necrosis factor alpha induces IL-4 production but has no direct additive impact on parasite burden in splenic cultures of human visceral leishmaniasis.
    by Neetu Singh, Shyam Sundar
    Published 2018-01-01
    “...Immune activating cytokines Interferon (IFN)-γ and Tumor necrosis factor (TNF)-α are known...”
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    Article
  3. 3
    Cytokine responses to novel antigens in an Indian population living in an area endemic for visceral leishmaniasis.
    “... preparations.Whole blood assays were employed to measure IFN-γ, TNF-α and IL-10 responses to peptide pools...”
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    Article
  4. 4
    Evaluation of Leishmania donovani protein disulfide isomerase as a potential immunogenic protein/vaccine candidate against visceral Leishmaniasis.
    “..., estimation of Th1 cytokines (IFN-γ and IL-12) as well as IL-10 in PBMCs of cured/endemic/infected Leishmania...”
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    Article
  5. 5
    Interferon-gamma release assay (modified QuantiFERON) as a potential marker of infection for Leishmania donovani, a proof of concept study.
    “... assay (IFN-γRA) as a novel marker for latent L. donovani infection.We modified a commercial kit...”
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    Article
  6. 6
    Characterization of glycolytic enzymes--rAldolase and rEnolase of Leishmania donovani, identified as Th1 stimulatory proteins, for their immunogenicity and immunoprophylactic efficacies against experimental visceral leishmaniasis.
    “... and generation of Th1-type cytokines (IFN-γ and IL-12) from stimulated PBMCs of cured/endemic VL patients...”
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    Article
  7. 7
    Th1 stimulatory proteins of Leishmania donovani: comparative cellular and protective responses of rTriose phosphate isomerase, rProtein disulfide isomerase and rElongation factor-2 in combination with rHSP70 against visceral leishmaniasis.
    “... with remarkable up-regulation of IFN-γ and IL-12 cytokines and extremely lower level of IL-4 and IL-10. Among...”
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    Article
  8. 8
    Nucleosomal histone proteins of L. donovani: a combination of recombinant H2A, H2B, H3 and H4 proteins were highly immunogenic and offered optimum prophylactic efficacy against Leishmania challenge in hamsters.
    “...-4) stimulated the production of Th1 cytokines IFN-γ, IL-12 and TNF-α but not Th2 cytokines IL-4...”
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    Article
  9. 9
    Imipramine is an orally active drug against both antimony sensitive and resistant Leishmania donovani clinical isolates in experimental infection.
    “... of the host protective factors TNF α, IFN γ and iNOS activity increased with the concomitant decrease in IL 10...”
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    Article
  10. 10
    Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology.
    “... caused by IFNγ-dependent TNF production. Therefore, we identify Blimp-1-dependent IL-10 produced by Tr1...”
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    Article
  11. 11
    Leishmania donovani: immunostimulatory cellular responses of membrane and soluble protein fractions of splenic amastigotes in cured patient and hamsters.
    “... lymphoproliferative, IFN-γ, IL-12 responses and Nitric Oxide production, in Leishmania-infected cured/exposed patients...”
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    Article
  12. 12
    Association of Interleukin-18 Gene Polymorphism with Susceptibility to Visceral Leishmaniasis in Endemic Area of Bihar, an Indian Population
    “...Interleukin-18 (IL-18) is a cytokine that mediates Th1 response by inducing interferon-gamma (IFN-γ...”
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    Article
  13. 13
    Combined Immune Therapy for the Treatment of Visceral Leishmaniasis.
    “... or parasite-specific IFNγ production. However, this treatment reversed the improved anti-parasitic immunity...”
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    Article
  14. 14
    Alcoholic Fractions F5 and F6 from Withania somnifera Leaves Show a Potent Antileishmanial and Immunomodulatory Activities to Control Experimental Visceral Leishmaniasis
    “... resulted in the reduction in IL-10, IL-4, and TGF-β mRNA expression and a significant increase in IFN-γ/IL...”
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    Article
  15. 15
    Assessing L. donovani Skin Parasite Load: A Proof of Concept Study of a Microbiopsy Device in an Indian Setting
    “... Test, rK39 ELISA, Whole Blood Analysis measuring IFN-γ and qPCR. A skin sample was collected...”
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    Article
  16. 16
    Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis
    “... of Leishmania donovani, a causative agent of human VL, associated with enhanced IFNγ but reduced IL-10...”
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    Article
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