Dual neonate vaccine platform against HIV-1 and M. tuberculosis.

by Richard Hopkins, Anne Bridgeman, Joan Joseph, Sarah C Gilbert, Helen McShane, Tomáš Hanke
Published 2011-01-01

Correction: Design and Pre-Clinical Evaluation of a Universal HIV-1 Vaccine

by Sven Létourneau, Eung-Jun Im, Tumelo Mashishi, Choechoe Brereton, Anne Bridgeman, Hongbing Yang, Lucy Dorrell, Tao Dong, Bette Korber, Andrew J. McMichael, Tomáš Hanke
Published 2011-01-01

Correction: Design and Pre-Clinical Evaluation of a Universal HIV-1 Vaccine.

by Sven Létourneau, Eung-Jun Im, Tumelo Mashishi, Choechoe Brereton, Anne Bridgeman, Hongbing Yang, Lucy Dorrell, Tao Dong, Bette Korber, Andrew J. McMichael, Tomáš Hanke
Published 2011-01-01

Priming With Recombinant BCG Expressing Novel HIV-1 Conserved Mosaic Immunogens and Boosting...

by Athina Kilpeläinen, Narcís Saubi, Núria Guitart, Nathifa Moyo, Edmund G. Wee, Krupa Ravi, Tomáš Hanke, Tomáš Hanke, Joan Joseph
Published 2019-05-01

Broad HIV-1 inhibition in vitro by vaccine-elicited CD8+ T cells in African adults

by Gaudensia Mutua, Bashir Farah, Robert Langat, Jackton Indangasi, Simon Ogola, Brian Onsembe, Jakub T Kopycinski, Peter Hayes, Nicola J Borthwick, Ambreen Ashraf, Len Dally, Burc Barin, Annika Tillander, Jill Gilmour, Jan De Bont, Alison Crook, Drew Hannaman, Josephine H Cox, Omu Anzala, Patricia E Fast, Marie Reilly, Kundai Chinyenze, Walter Jaoko, Tomáš Hanke
Published 2016-01-01

Specificity of CD8⁺ T-Cell Responses Following Vaccination with Conserved Regions of HIV-1 in Nairobi, Kenya

by Yehia S. Mohamed, Nicola J. Borthwick, Nathifa Moyo, Hayato Murakoshi, Tomohiro Akahoshi, Francesca Siliquini, Zara Hannoun, Alison Crook, Peter Hayes, Patricia E. Fast, Gaudensia Mutua, Walter Jaoko, Sandra Silva-Arrieta, Anuska Llano, Christian Brander, Masafumi Takiguchi, Tomáš Hanke
Published 2020-05-01

Efficient Induction of T Cells against Conserved HIV-1 Regions by Mosaic Vaccines Delivered as Self-Amplifying mRNA

by Nathifa Moyo, Annette B. Vogel, Søren Buus, Stephanie Erbar, Edmund G. Wee, Ugur Sahin, Tomáš Hanke
Published 2019-03-01

In vivo Effects of Romidepsin on T-Cell Activation, Apoptosis and Function in the BCN02 HIV-1 Kick&Kill Clinical Trial

by Miriam Rosás-Umbert, Miriam Rosás-Umbert, Marta Ruiz-Riol, Marco A. Fernández, Marta Marszalek, Pep Coll, Christian Manzardo, Samandhy Cedeño, José M. Miró, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, Tomáš Hanke, Tomáš Hanke, José Moltó, José Moltó, Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Christian Brander, Christian Brander, Christian Brander, the BCN02 study group, Susana Benet, Christian Brander, Samandhy Cedeño, Bonaventura Clotet, Pep Coll, Anuksa Llano, Javier Martinez-Picado, Marta Marszalek, Sara Morón-López, Beatriz Mothe, Roger Paredes, Maria C. Puertas, Miriam Rosás-Umbert, Marta Ruiz-Riol, Roser Escrig, Silvia Gel, Miriam López, Cristina Miranda, José Moltó, Jose Muñoz, Nuria Perez-Alvarez, Jordi Puig, Boris Revollo, Jessica Toro, Ana Maria Barriocanal, Magi Farré, Cristina Perez-Reche, Marta Valle, Christian Manzardo, Juan Ambrosioni, Irene Ruiz, Cristina Rovira, Carmen Ligero, Jose M. Miro, Antonio Carrillo, Michael Meulbroek, Ferran Pujol, Jorge Saz, Nicola Borthwick, Alison Crook, Edmund G. Wee, Tomáš Hanke
Published 2020-03-01

CD8+ T cells specific for conserved, cross-reactive Gag epitopes with strong ability to suppress HIV-1 replication

by Hayato Murakoshi, Chengcheng Zou, Nozomi Kuse, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, Tomáš Hanke, Masafumi Takiguchi
Published 2018-07-01

A Novel Vaccine Strategy Employing Serologically Different Chimpanzee Adenoviral Vectors for the Prevention of HIV-1 and HCV Coinfection

by Felicity Hartnell, Anthony Brown, Stefania Capone, Jakub Kopycinski, Carly Bliss, Shokouh Makvandi-Nejad, Leo Swadling, Emma Ghaffari, Paola Cicconi, Mariarosaria Del Sorbo, Roberta Sbrocchi, Ilaria Esposito, Ventzislav Vassilev, Paula Marriott, Clair M. Gardiner, Ciaran Bannan, Colm Bergin, Matthias Hoffmann, Bethany Turner, Alfredo Nicosia, Alfredo Nicosia, Alfredo Nicosia, Antonella Folgori, Tomáš Hanke, Tomáš Hanke, Eleanor Barnes, Eleanor Barnes, Lucy Dorrell, Lucy Dorrell
Published 2019-01-01

HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers.

by Silvia Capucci, Edmund G Wee, Torben Schiffner, Celia C LaBranche, Nicola Borthwick, Albert Cupo, Jonathan Dodd, Hansi Dean, Quentin Sattentau, David Montefiori, Per J Klasse, Rogier W Sanders, John P Moore, Tomáš Hanke
Published 2017-01-01

Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study)

by Beatriz Mothe, Christian Manzardo, Alvaro Sanchez-Bernabeu, Pep Coll, Sara Morón-López, Maria C. Puertas, Miriam Rosas-Umbert, Patricia Cobarsi, Roser Escrig, Núria Perez-Alvarez, Irene Ruiz, Cristina Rovira, Michael Meulbroek, Alison Crook, Nicola Borthwick, Edmund G. Wee, Hongbing Yang, Jose M. Miró, Lucy Dorrell, Bonaventura Clotet, Javier Martinez-Picado, Christian Brander, Tomáš Hanke
Published 2019-05-01

Novel Nested Peptide Epitopes Recognized by CD4⁺ T Cells Induced by HIV-1 Conserved-Region Vaccines

by Nicola Borthwick, Sandra Silva-Arrieta, Anuska Llano, Masafumi Takiguchi, Christian Brander, Tomáš Hanke
Published 2020-01-01

Effect of epitope variant co-delivery on the depth of CD8 T cell responses induced by HIV-1 conserved mosaic vaccines

by Edmund G. Wee, Nathifa Moyo, Zara Hannoun, Elena E. Giorgi, Bette Korber, Tomáš Hanke
Published 2021-06-01

Novel, in-natural-infection subdominant HIV-1 CD8+ T-cell epitopes revealed in human recipients of conserved-region T-cell vaccines.

by Nicola Borthwick, Zhansong Lin, Tomohiro Akahoshi, Anuska Llano, Sandra Silva-Arrieta, Tina Ahmed, Lucy Dorrell, Christian Brander, Hayato Murakoshi, Masafumi Takiguchi, Tomáš Hanke
Published 2017-01-01

HIVconsv Vaccines and Romidepsin in Early-Treated HIV-1-Infected Individuals: Safety, Immunogenicity and Effect on the Viral Reservoir (Study BCN02)

by Beatriz Mothe, Beatriz Mothe, Beatriz Mothe, Miriam Rosás-Umbert, Miriam Rosás-Umbert, Pep Coll, Christian Manzardo, Maria C. Puertas, Sara Morón-López, Anuska Llano, Cristina Miranda, Samandhy Cedeño, Miriam López, Yovaninna Alarcón-Soto, Guadalupe Gómez Melis, Klaus Langohr, Ana M. Barriocanal, Ana M. Barriocanal, Jessica Toro, Irene Ruiz, Cristina Rovira, Antonio Carrillo, Michael Meulbroek, Alison Crook, Edmund G. Wee, Jose M. Miró, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, Bonaventura Clotet, Marta Valle, Marta Valle, Javier Martinez-Picado, Javier Martinez-Picado, Javier Martinez-Picado, Tomáš Hanke, Tomáš Hanke, Christian Brander, Christian Brander, Christian Brander, José Moltó, José Moltó, The BCN02 Study Investigators
Published 2020-05-01

Tetravalent Immunogen Assembled from Conserved Regions of HIV-1 and Delivered as mRNA Demonstrates Potent Preclinical T-Cell Immunogenicity and Breadth

by Nathifa Moyo, Edmund G. Wee, Bette Korber, Kapil Bahl, Samantha Falcone, Sunny Himansu, Adrianne L. Wong, Antu K. Dey, Mark Feinberg, Tomáš Hanke
Published 2020-07-01

Priming with Recombinant BCG Expressing HTI Enhances the Magnitude and Breadth of the T-Cell Immune Responses Elicited by MVA.HTI in BALB/c Mice

by Narcís Saubi, Athina Kilpeläinen, Yoshiki Eto, Chun-Wei Chen, Àlex Olvera, Tomáš Hanke, Christian Brander, Joan Joseph-Munné
Published 2020-11-01

Long-term follow up of human T-cell responses to conserved HIV-1 regions elicited by DNA/simian adenovirus/MVA vaccine regimens.

by Nathifa Moyo, Nicola J Borthwick, Edmund G Wee, Silvia Capucci, Alison Crook, Lucy Dorrell, Tomáš Hanke
Published 2017-01-01

Randomized phase I trial HIV-CORE 003: Depletion of serum amyloid P component and immunogenicity of DNA vaccination against HIV-1.

by Nicola J Borthwick, Thirusha Lane, Nathifa Moyo, Alison Crook, Jung Min Shim, Ian Baines, Edmund G Wee, Philip N Hawkins, Julian D Gillmore, Tomáš Hanke, Mark B Pepys
Published 2018-01-01