Doing trials within trials: a qualitative study of stakeholder views on barriers and facilitators to the routine adoption of methodology research in clinical trials

by Jo Rick, Mike Clarke, Alan A. Montgomery, Paul Brocklehurst, Rachel Evans, Peter Bower
Published 2018-09-01

Global health trials methodological research agenda: results from a priority setting exercise

by Anna Rosala-Hallas, Aneel Bhangu, Jane Blazeby, Louise Bowman, Mike Clarke, Trudie Lang, Mona Nasser, Nandi Siegfried, Karla Soares-Weiser, Matt R. Sydes, Duolao Wang, Junhua Zhang, Paula R. Williamson
Published 2018-02-01

A rapid research needs appraisal methodology to identify evidence gaps to inform clinical research...

by Louise Sigfrid, Catrin Moore, Alex P. Salam, Nicola Maayan, Candyce Hamel, Chantelle Garritty, Vittoria Lutje, Brian Buckley, Karla Soares-Weiser, Rachel Marshall, Mike Clarke, Peter Horby
Published 2019-06-01

Identifying research priorities for effective retention strategies in clinical trials

by Anna Kearney, Anne Daykin, Alison R. G. Shaw, Athene J. Lane, Jane M. Blazeby, Mike Clarke, Paula Williamson, Carrol Gamble
Published 2017-08-01

Choosing important health outcomes for comparative effectiveness research: a systematic review.

by Elizabeth Gargon, Binu Gurung, Nancy Medley, Doug G Altman, Jane M Blazeby, Mike Clarke, Paula R Williamson
Published 2014-01-01

Identifying trial recruitment uncertainties using a James Lind Alliance Priority Setting Partnership – the PRioRiTy (Prioritising Recruitment in Randomised Trials) study

by Patricia Healy, Sandra Galvin, Paula R. Williamson, Shaun Treweek, Caroline Whiting, Beccy Maeso, Christopher Bray, Peter Brocklehurst, Mary Clarke Moloney, Abdel Douiri, Carrol Gamble, Heidi R. Gardner, Derick Mitchell, Derek Stewart, Joan Jordan, Martin O’Donnell, Mike Clarke, Sue H. Pavitt, Eleanor Woodford Guegan, Amanda Blatch-Jones, Valerie Smith, Hannah Reay, Declan Devane
Published 2018-03-01

‘Recruitment, recruitment, recruitment’ – the need for more focus on retention: a qualitative study of five trials

by Anne Daykin, Clare Clement, Carrol Gamble, Anna Kearney, Jane Blazeby, Mike Clarke, J. Athene Lane, Alison Shaw
Published 2018-01-01

Assessing the relevance and uptake of core outcome sets (an agreed minimum collection of outcomes to measure in research studies) in Cochrane systematic reviews: a review

by Karen Hughes, Mike Clarke, Sarah L Gorst, Paula R Williamson, Ricardo de Ávila Oliveira, Ian J Saldanha, Jochen Schmitt
Published 2020-09-01

Accumulating research: a systematic account of how cumulative meta-analyses would have provided knowledge, improved health, reduced harm and saved resources.

by Mike Clarke, Anne Brice, Iain Chalmers
Published 2014-01-01

Obtaining and managing data sets for individual participant data meta-analysis: scoping review and practical guide

by Matthew Ventresca, Holger J. Schünemann, Fergus Macbeth, Mike Clarke, Lehana Thabane, Gareth Griffiths, Simon Noble, David Garcia, Maura Marcucci, Alfonso Iorio, Qi Zhou, Mark Crowther, Elie A. Akl, Gary H. Lyman, Viktoria Gloy, Marcello DiNisio, Matthias Briel
Published 2020-05-01

Inconsistencies in the drawing and interpretation of smiley faces: an observational study

by Mike Clarke, Helen McAneney, Fiona Chan, Lisa Maguire
Published 2018-01-01

Learning from Cochrane systematic reviews: what improvements do these suggest for the design of trials? [version 2; peer review: 2 approved]

by Stefania Pirosca, Mike Clarke, Shaun Treweek
Published 2020-06-01

Evidence for public health on novel psychoactive substance use: a mixed-methods study

by Kathryn Higgins, Nina O’Neill, Leeanne O’Hara, Julie-Ann Jordan, Mark McCann, Tara O’Neill, Mike Clarke, Tony O’Neill, Anne Campbell
Published 2019-08-01

The COMET Handbook: version 1.0

by Paula R. Williamson, Douglas G. Altman, Heather Bagley, Karen L. Barnes, Jane M. Blazeby, Sara T. Brookes, Mike Clarke, Elizabeth Gargon, Sarah Gorst, Nicola Harman, Jamie J. Kirkham, Angus McNair, Cecilia A. C. Prinsen, Jochen Schmitt, Caroline B. Terwee, Bridget Young
Published 2017-06-01

Trial Forge Guidance 2: how to decide if a further Study Within A Trial (SWAT) is needed

by Shaun Treweek, Simon Bevan, Peter Bower, Matthias Briel, Marion Campbell, Jacquie Christie, Clive Collett, Seonaidh Cotton, Declan Devane, Adel El Feky, Sandra Galvin, Heidi Gardner, Katie Gillies, Kerenza Hood, Jan Jansen, Roberta Littleford, Adwoa Parker, Craig Ramsay, Lynne Restrup, Frank Sullivan, David Torgerson, Liz Tremain, Erik von Elm, Matthew Westmore, Hywel Williams, Paula R. Williamson, Mike Clarke
Published 2020-01-01

Core Outcome Set-STAndardised Protocol Items: the COS-STAP Statement

by Jamie J. Kirkham, Sarah Gorst, Douglas G. Altman, Jane M. Blazeby, Mike Clarke, Sean Tunis, Paula R. Williamson, for the COS-STAP Group
Published 2019-02-01

Partially systematic thoughts on the history of systematic reviews

by Mike Clarke
Published 2018-10-01

GAP: From Sound Design to Practical Implementation in Clinical Trials for Traditional Chinese Medicine

by Hongcai Shang, Boli Zhang, Zhaoxiang Bian, Youping Li, Mike Clarke, Nicola Robinson
Published 2014-01-01

Perceived barriers and facilitators to Risk Based Monitoring in academic-led clinical trials: a mixed methods study

by Caroline Hurley, Carol Sinnott, Mike Clarke, Patricia Kearney, Emmy Racine, Joseph Eustace, Frances Shiely
Published 2017-09-01

Early switch from intravenous to oral antibiotic therapy in patients with cancer who have low-risk neutropenic sepsis (the EASI-SWITCH trial): study protocol for a randomised contr...

by Caroline Forde, Ronan McMullan, Mike Clarke, Richard H. Wilson, Ruth Plummer, Margaret Grayson, Cliona McDowell, Ashley Agus, Annmarie Doran, Danny F. McAuley, Anne L. Thomas, Rosemary A. Barnes, Richard Adams, Ian Chau, Vicky Coyle
Published 2020-05-01