Novel formulation of a methotrexate derivative with a lipid nanoemulsion

by Moura JA, Valduga CJ, Tavares ER, Kretzer IF, Maria DA, Maranhao RC
Published 2011-10-01

Bone marrow mesenchymal stem cells and their derived exosomes resolve doxorubicin-induced chemobrain: critical role of their miRNA cargo

by Marwa O. El-Derany, Mohamed H. Noureldein
Published 2021-06-01

Targeted Delivery Prodigiosin to Choriocarcinoma by Peptide-Guided Dendrigraft Poly-<span style="font-variant: small-caps">l</span>-lysines Nanoparticles

by Kai Zhao, Dan Li, Guogang Cheng, Baozhen Zhang, Jinyu Han, Jie Chen, Baobei Wang, Mengxia Li, Tianxia Xiao, Jian Zhang, Dongpo Zhou, Zheng Jin, Xiujun Fan
Published 2019-11-01

Improved solubility, dissolution rate, and oral bioavailability of main biflavonoids from Selaginella doederleinii extract by amorphous solid dispersion

by Bing Chen, Xuewen Wang, Yanyan Zhang, Kangping Huang, Hao Liu, Dafen Xu, Shaoguang Li, Qicai Liu, Jianyong Huang, Hong Yao, Xinhua Lin
Published 2020-01-01

Non-linear Dose Response of Lymphocyte Cell Lines to Microtubule Inhibitors

by Daria M. Potashnikova, Daria M. Potashnikova, Aleena A. Saidova, Aleena A. Saidova, Anna V. Tvorogova, Anna V. Tvorogova, Eugene V. Sheval, Ivan A. Vorobjev, Ivan A. Vorobjev, Ivan A. Vorobjev
Published 2019-04-01

Long Chain Omega-3 Polyunsaturated Fatty Acid Supplementation Alleviates Doxorubicin-Induced Depressive-Like Behaviors and Neurotoxicity in Rats: Involvement of Oxidative Stress an...

by Yan-Qin Wu, Rui-Li Dang, Mi-Mi Tang, Hua-Lin Cai, Huan-De Li, De-Hua Liao, Xin He, Ling-Juan Cao, Ying Xue, Pei Jiang
Published 2016-04-01

Protocatechuic aldehyde attenuates cisplatin-induced acute kidney injury by suppressing Nox-mediated oxidative stress and renal inflammation

by Li Gao, weifeng Wu, guiling Ren, haidi Li, qin Yang, xiaofeng Li, tao Xu, zeng Li, baoming Wu, taotao Ma, cheng Huang, dong Lei, yan Hang, lei Zhang, xiongwen Lv, Jun Li, Xiaoming Meng
Published 2016-12-01

Targeted Gold Nanohybrids Functionalized with Folate-Hydrophobic-Quaternized Pullulan Delivering Camptothecin for Enhancing Hydrophobic Anticancer Drug Efficacy

by Sakchai Laksee, Chamaiporn Supachettapun, Nongnuj Muangsin, Pattra Lertsarawut, Thitirat Rattanawongwiboon, Phitchan Sricharoen, Nunticha Limchoowong, Threeraphat Chutimasakul, Tanagorn Kwamman, Kasinee Hemvichian
Published 2021-08-01

LIM and SH3 protein 1 induces glioma growth and invasion through PI3K/AKT signaling and epithelial-mesenchymal transition

by Chuanhong Zhong, Xianglong Li, Bei Tao, Lilei Peng, Tangming Peng, Xiaobo Yang, Xiangguo Xia, Ligang Chen
Published 2019-08-01

Characterization of the Blood–Brain Barrier Integrity and the Brain Transport of SN-38 in an Orthotopic Xenograft Rat Model of Diffuse Intrinsic Pontine Glioma

by Catarina Chaves, Xavier Declèves, Meryam Taghi, Marie-Claude Menet, Joelle Lacombe, Pascale Varlet, Nagore G. Olaciregui, Angel M. Carcaboso, Salvatore Cisternino
Published 2020-04-01

Low Sucrose, Omega-3 Enriched Diet Has Region-Specific Effects on Neuroinflammation and Synaptic Function Markers in a Mouse Model of Doxorubicin-Based Chemotherapy

by Tonya S. Orchard, Monica M. Gaudier-Diaz, Panchita Phuwamongkolwiwat-Chu, Rebecca Andridge, Maryam B. Lustberg, Joshua Bomser, Rachel M. Cole, Martha A. Belury, A. Courtney DeVries
Published 2018-12-01

Synthesis and Biological Evaluation of New Pyridone-Annelated Isoindigos as Anti-Proliferative Agents

by Ayman M. Saleh, Randa M. Al-As'ad, Mustafa M. El-Abadelah, Salim S. Sabri, Jalal A. Zahra, Ahmed S. Alaskar, Ahmad Aljada
Published 2014-08-01

Genomic Subtypes of GISTs for Stratifying Patient Response to Sunitinib following Imatinib Resistance: A Pooled Analysis and Systematic Review

by Siyuan Tan, Ping Chen, Jiafu Ji, Shanshan Guo, Dapeng Yu, Tetsuya Asakawa, Yu Zhou, Masanobu Abe, Liang Zong
Published 2018-01-01

Loss-of-function mutations in the histone methyltransferase EZH2 promote chemotherapy resistance in AML

by Julia M. Kempf, Sabrina Weser, Michael D. Bartoschek, Klaus H. Metzeler, Binje Vick, Tobias Herold, Kerstin Völse, Raphael Mattes, Manuela Scholz, Lucas E. Wange, Moreno Festini, Enes Ugur, Maike Roas, Oliver Weigert, Sebastian Bultmann, Heinrich Leonhardt, Gunnar Schotta, Wolfgang Hiddemann, Irmela Jeremias, Karsten Spiekermann
Published 2021-03-01

Anti-Apoptotic Effects of Osteopontin via the Up-Regulation of AKT/mTOR/β-Catenin Loop in Acute Myeloid Leukemia Cells

by Mahdi Zahed Panah, Mohsen Nikbakht, Seyed Mehdi Sajjadi, Shahrbano Rostami, Amir Hossein Norooznezhad, Hosein Kamranzadeh Fumani, Ardeshir Ghavamzadeh, Saeed Mohammadi
Published 2017-04-01

Paclitaxel Enhances the Innate Immunity by Promoting NLRP3 Inflammasome Activation in Macrophages

by Qiong-zhen Zeng, Fan Yang, Chen-guang Li, Li-hui Xu, Xian-hui He, Feng-yi Mai, Chen-ying Zeng, Cheng-cheng Zhang, Qing-bing Zha, Dong-yun Ouyang
Published 2019-01-01

Characterization of Immune-Related Long Non-coding RNAs to Construct a Novel Signature and Predict the Prognosis and Immune Landscape of Soft Tissue Sarcoma

by Zhengjun Lin, Zhengjun Lin, Ke Pang, Hongli Li, Xianghong Zhang, Jia Wan, Tao Zheng, Tang Liu, Weijun Peng
Published 2021-09-01

Persistent accumulation of unrepaired DNA damage in rat cortical neurons: nuclear organization and ChIP-seq analysis of damaged DNA

by Jorge Mata-Garrido, Olga Tapia, Iñigo Casafont, Maria T. Berciano, Ana Cuadrado, Miguel Lafarga
Published 2018-07-01

Establishment of malignantly transformed dendritic cell line SU3-ihDCTC induced by Glioma stem cells and study on its sensitivity to resveratrol

by Xifeng Fei, Anqi Wang, Delin Wang, Xan Meng, Jiawei Ma, Lei Hong, Ruwei Qin, Aidong Wang, Jun Dong, Qiang Huang, Zhimin Wang
Published 2018-02-01

Grape seed proanthocyanidin extract reverses multidrug resistance in HL-60/ADR cells via inhibition of the PI3K/Akt signaling pathway

by Ka-Na Lin, Yue-Lian Jiang, Shun-Guo Zhang, Shi-Ying Huang, Hao Li
Published 2020-05-01