Spatial Gradient of Microstructural Changes in Normal-Appearing White Matter in Tracts Affected by White Matter Hyperintensities in Older Age

by Susana Muñoz Maniega, Susana Muñoz Maniega, Susana Muñoz Maniega, Rozanna Meijboom, Rozanna Meijboom, Rozanna Meijboom, Rozanna Meijboom, Francesca M. Chappell, Francesca M. Chappell, Maria del C. Valdés Hernández, Maria del C. Valdés Hernández, Maria del C. Valdés Hernández, John M. Starr, John M. Starr, Mark E. Bastin, Mark E. Bastin, Ian J. Deary, Ian J. Deary, Joanna M. Wardlaw, Joanna M. Wardlaw, Joanna M. Wardlaw
Published 2019-07-01

Correction: The Mechanical and Material Designs of Composite Ju|’hoansi Arrowheads

by Courtney Archer, Iain Campbell, Fraser Cheyne, Amos Lim Jun Meng, Csongor Senanszky, Dimitrios Mamalis, Colin Robert, Parvez Alam
Published 2020-10-01

Correction to: Efficacy of Mentalization-based group therapy for adolescents: the results of a pilot randomised controlled trial

by Helen Griffiths, Fiona Duffy, Louise Duffy, Sarah Brown, Harriet Hockaday, Emma Eliasson, Jessica Graham, Julie Smith, Alice Thomson, Matthias Schwannauer
Published 2021-03-01

Lamin A molecular compression and sliding as mechanisms behind nucleoskeleton elasticity

by Alex A. Makarov, Juan Zou, Douglas R. Houston, Christos Spanos, Alexandra S. Solovyova, Cristina Cardenal-Peralta, Juri Rappsilber, Eric C. Schirmer
Published 2019-07-01

Pre-40S ribosome biogenesis factor Tsr1 is an inactive structural mimic of translational GTPases

by Urszula M. McCaughan, Uma Jayachandran, Vadim Shchepachev, Zhuo Angel Chen, Juri Rappsilber, David Tollervey, Atlanta G. Cook
Published 2016-06-01

Pseudomonas expression of an oxygen sensing prolyl hydroxylase homologue regulates neutrophil host responses in vitro and in vivo [version 1; referees: 2 approved, 1 approved with...

by Rebecca S. Dickinson, Fiona Murphy, Catherine Doherty, Sam Williams, Ananda Mirchandani, Joseph Willson, John S. Scotti, Gail Preston, Christopher J. Schofield, Moira K.B. Whyte, Sarah R. Walmsley
Published 2017-10-01

Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells

by Céline Souilhol, Christèle Gonneau, Javier G. Lendinez, Antoniana Batsivari, Stanislav Rybtsov, Heather Wilson, Lucia Morgado-Palacin, David Hills, Samir Taoudi, Jennifer Antonchuk, Suling Zhao, Alexander Medvinsky
Published 2016-03-01

Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936

by Robert F. Hillary, Daniel L. McCartney, Sarah E. Harris, Anna J. Stevenson, Anne Seeboth, Qian Zhang, David C. Liewald, Kathryn L. Evans, Craig W. Ritchie, Elliot M. Tucker-Drob, Naomi R. Wray, Allan F. McRae, Peter M. Visscher, Ian J. Deary, Riccardo E. Marioni
Published 2019-07-01

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells

by Chris J. C. Johnston, Danielle J. Smyth, Ravindra B. Kodali, Madeleine P. J. White, Yvonne Harcus, Kara J. Filbey, James P. Hewitson, Cynthia S. Hinck, Alasdair Ivens, Andrea M. Kemter, Anna O. Kildemoes, Thierry Le Bihan, Dinesh C. Soares, Stephen M. Anderton, Thomas Brenn, Stephen J. Wigmore, Hannah V. Woodcock, Rachel C. Chambers, Andrew P. Hinck, Henry J. McSorley, Rick M. Maizels
Published 2017-11-01

RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways

by Victoria Gudiño, Sebastian Öther-Gee Pohl, Caroline V. Billard, Patrizia Cammareri, Alfonso Bolado, Stuart Aitken, David Stevenson, Adam E. Hall, Mark Agostino, John Cassidy, Colin Nixon, Alex von Kriegsheim, Paz Freile, Linda Popplewell, George Dickson, Laura Murphy, Ann Wheeler, Malcolm Dunlop, Farhat Din, Douglas Strathdee, Owen J. Sansom, Kevin B. Myant
Published 2021-04-01

Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936

by Jamie Toombs, Lindsay Panther, Loren Ornelas, Chunyan Liu, Emilda Gomez, Raquel Martín-Ibáñez, Simon R. Cox, Stuart J. Ritchie, Sarah E. Harris, Adele Taylor, Paul Redmond, Tom C. Russ, Lee Murphy, James D. Cooper, Karen Burr, Bhuvaneish T. Selvaraj, Cathy Browne, Clive N. Svendsen, Sally A. Cowley, Ian J. Deary, Siddharthan Chandran, Tara L. Spires-Jones, Dhruv Sareen
Published 2020-07-01

Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease

by N. T. Ventham, N. A. Kennedy, A. T. Adams, R. Kalla, S. Heath, K. R. O'Leary, H. Drummond, IBD BIOM consortium, IBD CHARACTER consortium, D. C. Wilson, I. G. Gut, E. R. Nimmo, J. Satsangi
Published 2016-11-01

Kynurenine 3-monooxygenase is a critical regulator of renal ischemia–reperfusion injury

by Xiaozhong Zheng, Ailiang Zhang, Margaret Binnie, Kris McGuire, Scott P. Webster, Jeremy Hughes, Sarah E. M. Howie, Damian J. Mole
Published 2019-02-01

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences

by Sean McKay, Tomás J. Ryan, Jamie McQueen, Tim Indersmitten, Katie F.M. Marwick, Philip Hasel, Maksym V. Kopanitsa, Paul S. Baxter, Marc-André Martel, Peter C. Kind, David J.A. Wyllie, Thomas J. O’Dell, Seth G.N. Grant, Giles E. Hardingham, Noboru H. Komiyama
Published 2018-10-01

RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit

by Laura Milligan, Camille Sayou, Alex Tuck, Tatsiana Auchynnikava, Jane EA Reid, Ross Alexander, Flavia de Lima Alves, Robin Allshire, Christos Spanos, Juri Rappsilber, Jean D Beggs, Grzegorz Kudla, David Tollervey
Published 2017-10-01

Epigenetic modification of the PD-1 (Pdcd1) promoter in effector CD4+ T cells tolerized by peptide immunotherapy

by Rhoanne C McPherson, Joanne E Konkel, Catriona T Prendergast, John P Thomson, Raffaele Ottaviano, Melanie D Leech, Oliver Kay, Stephanie E J Zandee, Claire H Sweenie, David C Wraith, Richard R Meehan, Amanda J Drake, Stephen M Anderton
Published 2014-12-01

Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome

by Robert L. Hollis, John P. Thomson, Barbara Stanley, Michael Churchman, Alison M. Meynert, Tzyvia Rye, Clare Bartos, Yasushi Iida, Ian Croy, Melanie Mackean, Fiona Nussey, Aikou Okamoto, Colin A. Semple, Charlie Gourley, C. Simon Herrington
Published 2020-10-01

TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing

by Theresa Schöpp, Ansgar Zoch, Rebecca V. Berrens, Tania Auchynnikava, Yuka Kabayama, Lina Vasiliauskaitė, Juri Rappsilber, Robin C. Allshire, Dónal O’Carroll
Published 2020-07-01

Characterisation of the British honey bee metagenome

by Tim Regan, Mark W. Barnett, Dominik R. Laetsch, Stephen J. Bush, David Wragg, Giles E. Budge, Fiona Highet, Benjamin Dainat, Joachim R. de Miranda, Mick Watson, Mark Blaxter, Tom C. Freeman
Published 2018-11-01

Livestock 2.0 – genome editing for fitter, healthier, and more productive farmed animals

by Christine Tait-Burkard, Andrea Doeschl-Wilson, Mike J. McGrew, Alan L. Archibald, Helen M. Sang, Ross D. Houston, C. Bruce Whitelaw, Mick Watson
Published 2018-11-01