Article metabolism controlled study 45 human 44 Computational Biology 42 Humans 42 biology 42 nonhuman 35 genetics 33 chemistry 27 Animals 26 animal 26 biological model 25 physiology 22 Models, Biological 18 mathematical model 16 procedures 16 drug effect 15 prediction 15 male 14 molecular dynamics 14 unclassified drug 14 algorithm 13 Male 12 mouse 12 protein binding 12 simulation 12 Mice 11 Protein Binding 11 computer simulation 11