adult human 100 Article 94 Humans 88 controlled study 86 female 84 male 82 genetics 81 Female 61 Male 58 gene expression 58 middle aged 58 unclassified drug 56 Middle Aged 55 gene expression regulation 52 metabolism 51 major clinical study 50 human tissue 45 Adult 41 down regulation 41 upregulation 40 pathology 39 aged 37 Gene Expression Regulation, Neoplastic 36 human cell 31 protein expression 30 Aged 28 real time polymerase chain reaction 28 microRNA 27 MicroRNAs 24