controlled study 157 male 146 nonhuman 140 Article 133 animal experiment 127 animal model 125 Animals 94 Male 92 human 92 MODEL 89 Malaysia 85 rat 85 animal tissue 81 Humans 79 animal 78 female 77 unclassified drug 77 article 64 Female 57 metabolism 56 chemistry 55 mouse 50 plant extract 49 priority journal 48 Rats 46 adult 45 drug effect 41 Rats, Sprague-Dawley 39 plant leaf 33 statistical model 33