Article 2 Humans 2 Models, Biological 2 Signal Transduction 2 biological model drug effect human 2 mathematical model metabolism signal transduction 2 5 chloro 4 [[2 (isopropylsulfonyl)phenyl]amino] 2 [[2 methoxy 4 [4 (4 methyl 1 piperazinyl) 1 piperidinyl]phenyl]amino]pyrimidine 1 8 [4 (1 aminocyclobutyl)phenyl] 9 phenyl 1,2,4 triazolo[3,4 f][1,6]naphthyridin 3(2h) one 1 Antineoplastic Agents 1 Antineoplastic Combined Chemotherapy Protocols 1 Atorvastatin 1 CHP212 cell line 1 Cell Line, Tumor 1 Cell Proliferation 1 Cognitive Dysfunction 1 Computational Biology 1 Cytokines 1 Drug Resistance, Neoplasm 1 Drug Screening Assays, Antitumor 1 Feedback 1 IMR-32 cell line 1 Kelly cell line 1 LAN6 cell line 1 MAP Kinase Signaling System 1 MAPK signaling 1 N206 cell line 1