Article 13 controlled study female 13 human 13 major clinical study adult 12 male 12 middle aged 11 Humans 10 Female 9 Middle Aged 9 aged 9 receiver operating characteristic 9 Male 8 sensitivity and specificity 8 diagnostic test accuracy study 7 Adult 6 blood 6 Aged 5 area under the curve 5 very elderly 5 Biomarkers, Tumor 4 Case-Control Studies 4 Prognosis 4 case control study 4 follow up 4 mortality 4 prediction 4 prognosis 4 protein blood level 4