Selective therapeutic strategy for p53-deficient cancer by targeting dysregulation in DNA repair

by Justin Zonneville, Moyi Wang, Mohammed M. Alruwaili, Brandon Smith, Megan Melnick, Kevin H. Eng, Thomas Melendy, Ben Ho Park, Renuka Iyer, Christos Fountzilas, Andrei V. Bakin
Published 2021-07-01

Breaking down discipline barriers: an interview with Maël Lebreton on starting a career in an interdisciplinary field

Published 2021-07-01

Mutation in FBXO32 causes dilated cardiomyopathy through up-regulation of ER-stress mediated apoptosis

by Nadya Al-Yacoub, Dilek Colak, Salma Awad Mahmoud, Maya Hammonds, Kunhi Muhammed, Olfat Al-Harazi, Abdullah M. Assiri, Jehad Al-Buraiki, Waleed Al-Habeeb, Coralie Poizat
Published 2021-07-01

Publisher Correction: Deletion of the diabetes candidate gene Slc16a13 in mice attenuates diet-induced ectopic lipid accumulation and insulin resistance

by Tina Schumann, Jörg König, Christian von Loeffelholz, Daniel F. Vatner, Dongyan Zhang, Rachel J. Perry, Michel Bernier, Jason Chami, Christine Henke, Anica Kurzbach, Nermeen N. El-Agroudy, Diana M. Willmes, Dominik Pesta, Rafael de Cabo, John F. O´Sullivan, Eric Simon, Gerald I. Shulman, Bradford S. Hamilton, Andreas L. Birkenfeld
Published 2021-07-01

Cocaine self-administration induces sex-dependent protein expression in the nucleus accumbens

by Alberto J. López, Amy R. Johnson, Tanner J. Euston, Rashaun Wilson, Suzanne O. Nolan, Lillian J. Brady, Kimberly C. Thibeault, Shannon J. Kelly, Veronika Kondev, Patrick Melugin, M. Gunes Kutlu, Emily Chuang, TuKiet T. Lam, Drew D. Kiraly, Erin S. Calipari
Published 2021-07-01

Single-molecule imaging and microfluidic platform reveal molecular mechanisms of leukemic cell rolling

by Bader Al Alwan, Karmen AbuZineh, Shuho Nozue, Aigerim Rakhmatulina, Mansour Aldehaiman, Asma S. Al-Amoodi, Maged F. Serag, Fajr A. Aleisa, Jasmeen S. Merzaban, Satoshi Habuchi
Published 2021-07-01

Non-flipping DNA glycosylase AlkD scans DNA without formation of a stable interrogation complex

by Arash Ahmadi, Katharina Till, Paul Hoff Backe, Pernille Blicher, Robin Diekmann, Mark Schüttpelz, Kyrre Glette, Jim Tørresen, Magnar Bjørås, Alexander D. Rowe, Bjørn Dalhus
Published 2021-07-01

Neutrophil-derived reactive oxygen species promote tumor colonization

by Jianghong Zhong, Qijing Li, Huqiao Luo, Rikard Holmdahl
Published 2021-07-01

Leukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants

by Mariangela Cavarelli, Stéphane Hua, Naima Hantour, Sabine Tricot, Nicolas Tchitchek, Céline Gommet, Hakim Hocini, Catherine Chapon, Nathalie Dereuddre-Bosquet, Roger Le Grand
Published 2021-07-01

An implantable human stem cell-derived tissue-engineered rostral migratory stream for directed neuronal replacement

by John C. O’Donnell, Erin M. Purvis, Kaila V. T. Helm, Dayo O. Adewole, Qunzhou Zhang, Anh D. Le, D. Kacy Cullen
Published 2021-07-01

Cuticular modified air sacs underlie white coloration in the olive fruit fly, Bactrocera oleae

by Manuela Rebora, Gianandrea Salerno, Silvana Piersanti, Alexander Kovalev, Stanislav Gorb
Published 2021-07-01

Large-scale phenotyping of 1,000 fungal strains for the degradation of non-natural, industrial compounds

by David Navarro, Delphine Chaduli, Sabine Taussac, Laurence Lesage-Meessen, Sacha Grisel, Mireille Haon, Philippe Callac, Régis Courtecuisse, Cony Decock, Joëlle Dupont, Florence Richard-Forget, Jacques Fournier, Jacques Guinberteau, Christian Lechat, Pierre-Arthur Moreau, Laetitia Pinson-Gadais, Bernard Rivoire, Lucile Sage, Stéphane Welti, Marie-Noëlle Rosso, Jean-Guy Berrin, Bastien Bissaro, Anne Favel
Published 2021-07-01

Identification of a pathway for electron uptake in Shewanella oneidensis

by Annette R. Rowe, Farshid Salimijazi, Leah Trutschel, Joshua Sackett, Oluwakemi Adesina, Isao Anzai, Liat H. Kugelmass, Michael H. Baym, Buz Barstow
Published 2021-08-01

Gastrobodies are engineered antibody mimetics resilient to pepsin and hydrochloric acid

by Niels Wicke, Mike R. Bedford, Mark Howarth
Published 2021-08-01

Predicting the taxonomic and environmental sources of integron gene cassettes using structural and sequence homology of attC sites

by Timothy M. Ghaly, Sasha G. Tetu, Michael R. Gillings
Published 2021-08-01

Glycans housed by a bacteriophage enable rapid identification of glycan recognition patterns

by Theam Soon Lim, Karli Montague-Cardoso
Published 2021-08-01

An essential role of acetyl coenzyme A in the catalytic cycle of insect arylalkylamine N-acetyltransferase

by Chu-Ya Wu, I-Chen Hu, Yi-Chen Yang, Wei-Cheng Ding, Chih-Hsuan Lai, Yi-Zong Lee, Yi-Chung Liu, Hui-Chun Cheng, Ping-Chiang Lyu
Published 2020-08-01

Estrogen mediates sex differences in preoptic neuropeptide and pituitary hormone production in medaka

by Junpei Yamashita, Yuji Nishiike, Thomas Fleming, Daichi Kayo, Kataaki Okubo
Published 2021-08-01

A fragment-based approach identifies an allosteric pocket that impacts malate dehydrogenase activity

by Atilio Reyes Romero, Serjey Lunev, Grzegorz M. Popowicz, Vito Calderone, Matteo Gentili, Michael Sattler, Jacek Plewka, Michał Taube, Maciej Kozak, Tad A. Holak, Alexander S. S. Dömling, Matthew R. Groves
Published 2021-08-01

At the frontline of COVID research: an interview with Akiko Iwasaki on her groundbreaking COVID projects and advocacy for women and minorities in STEM

Published 2021-08-01