Adult Humans 4 adult 4 genetics 4 human 4 Article 3 Male 3 female 3 male 3 Aged 2 Case-Control Studies 2 China 2 Female 2 Genetic Predisposition to Disease 2 High-Throughput Nucleotide Sequencing 2 Middle Aged 2 Polymorphism, Single Nucleotide 2 aged 2 bioinformatics 2 case control study 2 controlled study 2 follow up 2 gene frequency 2 gene sequence 2 genetic predisposition 2 high throughput sequencing 2 major clinical study 2 metabolism 2 middle aged 2 single nucleotide polymorphism 2