Article coronavirus disease 2019 442 human 431 COVID-19 372 Humans 330 SARS-CoV-2 245 female 234 pandemic 231 male 221 adult 219 controlled study 184 major clinical study 150 Pandemics 123 Female 121 middle aged 113 Male 111 aged 107 Severe acute respiratory syndrome coronavirus 2 86 Adult 85 epidemiology 84 Middle Aged 82 nonhuman 61 Aged 60 United States 59 disease severity 59 clinical article 58 procedures 57 questionnaire 56 cohort analysis 55 retrospective study 55