Article controlled study 198 human 187 genetics 156 Humans 154 gene expression 135 metabolism 122 unclassified drug 120 nonhuman 115 gene expression regulation 114 male 112 female 104 upregulation 96 adult 94 down regulation 92 human cell 89 protein expression 84 pathology 73 human tissue 71 Female 69 Male 68 Gene Expression Regulation, Neoplastic 62 Animals 61 animal 61 animal experiment 60 real time polymerase chain reaction 59 major clinical study 57 middle aged 55 cell proliferation 52 Middle Aged 51