Adipates 2 Angiotensin-Converting Enzyme 2 2 COVID-19 2 Humans MM-PBSA 2 Molecular Dynamics Simulation 2 Mutation 2 Protein Binding 2 SARS-CoV-2 2 Spike Glycoprotein, Coronavirus 2 Succinates 2 VoC’s 2 adipic acid 2 compensatory mutations 2 coronavirus spike glycoprotein 2 gamma variant 2 genetics 2 human 2 metabolism 2 molecular dynamics 2 mutation 2 poly(tetramethylene succinate-co-tetramethylene adipate) 2 protein binding 2 residue specific interaction entropy 2 spike protein, SARS-CoV-2 2 succinic acid derivative 2