Humans disease association human 170 Article 154 female 145 male 131 adult 126 Female 116 major clinical study 111 controlled study 101 Male 100 Adult 84 middle aged 83 Middle Aged 76 aged 64 Aged 45 adolescent 43 young adult 41 risk factor 40 Adolescent 39 complication 39 disease severity 38 Young Adult 36 follow up 34 priority journal 32 cohort analysis 31 psychology 31 cross-sectional study 30 child 27 genetics 27