Article 3 Case-Control Studies 3 Female 3 Humans Male 3 Middle Aged 3 adult 3 case control study 3 controlled study 3 female 3 human 3 major clinical study 3 male 3 middle aged Biomarkers 2 Follow-Up Studies 2 Prognosis 2 biological marker 2 blood 2 chronic kidney failure 2 disease association 2 enzyme linked immunosorbent assay 2 follow up 2 gene expression 2 metabolism 2 prognosis 2 protein blood level 2 protein expression 2 real time polymerase chain reaction 2 receiver operating characteristic 2