Humans human 203 Article 130 controlled study 111 metabolism 111 genetics 86 female 77 male 77 Female 68 Male 66 adult 66 enzyme linked immunosorbent assay 65 unclassified drug 55 chemistry 50 middle aged 49 nonhuman 48 Middle Aged 47 human cell 44 major clinical study 44 Adult 42 Animals 37 drug effect 37 animal 36 pathology 36 biological marker 34 protein expression 32 Biomarkers 31 aged 31 Aged 28 COVID-19 28