Article 14 Female 14 Humans 14 Male Severity of Illness Index female 14 human 14 major clinical study male 14 risk factor severity of illness index 14 Middle Aged 13 adult 13 middle aged 13 controlled study 12 disease severity 12 Adult 8 Aged 8 Risk Factors 8 aged 8 pathology 7 blood 6 Case-Control Studies 5 case control study 5 disease association 5 receiver operating characteristic 5 risk assessment 5 Retrospective Studies 4 age 4 clinical feature 4