Cefotaxime 1 Column liquid chromatography 1 Eudragit 1 PH-Sensitive nanoparticles accuracy 1 acetic acid 1 ammonium acetate 1 analytic method 1 aqueous solution 1 article 1 cefotaxime 1 concentration (parameters) 1 controlled study 1 drug determination 1 flow rate 1 liquid chromatography 1 nanoparticle 1 pH 1 phase transition 1 priority journal 1 sensitivity analysis 1 sensitivity and specificity 1 validation process 1