CRISPR Cas system 2 CRISPR-Cas Systems 2 Gene Editing 2 Prime editing gene editing 2 Animals 1 Base editing 1 CRISPR-Cas9 1 Clustered Regularly Interspaced Short Palindromic Repeats 1 Cytosine 1 Deoxyribonuclease I 1 Effector domains 1 End effectors 1 Francisella 1 Francisella novicida 1 Guide RNA design 1 Humans 1 Multiple targets 1 Ortholog 1 Publicly accessible 1 RNA directed DNA polymerase 1 RNA, Guide 1 RNA-Directed DNA Polymerase 1 Rapid expansion 1 Reagents 1 Reverse transcriptases 1 Target expansion 1 User friendly design 1 WEB application 1 Web application 1