Patient treatment 2 Progressive disease 18-f-fluorodeoxyglucose 1 Amino acids 1 Apparent diffusion coefficient 1 Biomechanics 1 Botulinum toxin 1 Botulinum toxins 1 Computerized tomography 1 Contrast-enhanced CT 1 Diffusion weighted imaging 1 Enzyme inhibition 1 FDG PET/CT 1 Functional parameters 1 Gait analysis 1 Gastrointestinal stromal tumor 1 Gastrointestinal stromal tumors 1 Joint loads 1 Joints (anatomy) 1 KOOS 1 Knee osteoarthritis 1 Magnetic resonance imaging 1 Management options 1 Muscle 1 Musculoskeletal simulation 1 Patient case 1 Patient monitoring 1 Positron emission tomography 1 Surface diffusion 1 Translational Research 1