Biocompatibility 1 Controlled drug delivery 1 Controlled drug release 1 Drug interactions 1 Drug loading 1 Drug-delivery systems 1 Dynamic studies 1 Fourier transform infrared spectroscopy 1 Hydrogen bonds 1 Ketoprofen 1 Medical applications 1 Molecular dynamics 1 Silica 1 Silica based materials Sol'gel 1 Sols 1 Surface interactions 1 Synthesised 1 Targeted drug delivery 1 Theoretical study 1 adsorption 1 biomaterials 1 drug delivery 1 drug loading 1 ketoprofen 1 molecular dynamics simulations 1 silica-based materials 1 surface interactions 1