Passive transfer of Ad26.COV2.S-elicited IgG from humans attenuates SARS-CoV-2 disease in hamsters

by Andersen, H., Ansel, J.L, Barouch, D.H, Barrett, J., Bradette, H., Cayer, K., Chandrashekar, A., Chang, A., Cox, F., de Groot, A.M, Gardner, S., Heerwegh, D., Holman, S., Jacob-Dolan, C., Jaegle, K., Kar, S., Le Gars, M., Lewis, M.G, Lok, M., Nase, D., Patel, S., Porto, M., Powers, O.C, Sadoff, J., Sanborn, O., Schuitemaker, H., Seaman, M.S, Sellers, D., Spence, B., Stephenson, K.E, Tolboom, J.T.B.M, Tostanoski, L.H, Wegmann, F., Yu, J., Zahn, R.C
Published 2022

Microfluidic Squeezing Enables MHC Class I Antigen Presentation by Diverse Immune Cells to Elicit CD8+ T Cell Responses with Antitumor Activity

by Abdeljawad, T., An, H., Bernstein, H., Blagovic, K., Booty, M.G, Chong, E., Chow, J., Gonzalez, J.T, Heimann, M., Hlavaty, K.A, How, E., Jacques, M.K, Jensen, K.F, Knoetgen, H., Langer, R., Liu, S., Loughhead, S.M, Mao, S., Merino, A., Myint, M., Ozay, E.I, Pomerance, L., Pryor, O., Sharei, A., Smith, C., Stockmann, A., Subramanya, D., Talarico, L., Tian, L., Trumpfheller, C., Umaña, P., Venkitaraman, A., Vicente-Suarez, I., Volk, K., von Andrian, U.H, Yarar, D., Yee, C.
Published 2022

HIF activation enhances FcγRIIb expression on mononuclear phagocytes impeding tumor targeting antibody immunotherapy

by Beers, S.A, Booth, S.G, Carter, M.J, Chee, S.J, Cleary, K.L.S, Cragg, M.S, Cutress, R.I, Dahal, L.N, Douglas, J., Foxall, R.B, French, R.R, Frendéus, B., Ghorbani, M., Glennie, M.J, Hargreaves, C.E, Hussain, K., James, S., Kemp, R.S, Liu, R., Longley, J., Macari, S., Markham, H., Müller, K.T.J, Murray, T., Oldham, R.J, Ottensmeier, C.H, Roghanian, A., Smith, R.C.G, Stopforth, R.J, Strefford, J.C, Thirdborough, S.M
Published 2022

G6PD functions as a metabolic checkpoint to regulate granzyme B expression in tumor-specific cytotoxic T lymphocytes

by Colby, A.H, Colson, Y.L, Ding, H.-F, Grinstaff, M.W, Klement, J.D, Liu, K., Lu, C., Oberlies, N.H, Pearce, C.J, Shi, H., Yang, D.
Published 2022