adult human 9 Humans 5 article 5 controlled study 5 female 5 Adult 4 Male 4 Middle Aged 4 male 4 middle aged 4 Article 3 China 3 Female 3 child 3 Adolescent 2 Aged 2 Follow-Up Studies 2 High-Throughput Nucleotide Sequencing 2 Prognosis 2 Young Adult 2 adolescent 2 aged 2 bioinformatics 2 clinical article 2 follow up 2 gene sequence 2 genetics 2 high throughput sequencing 2 infant 2