Article 3 Female 3 Humans 3 Male 3 United States 3 cohort analysis 3 controlled study economics female 3 health care cost 3 human 3 major clinical study 3 male 3 Aged 2 Cohort Studies 2 Cost of Illness 2 Databases, Factual 2 ICD-10-CM 2 ICD-9-CM 2 Insurance Claim Review 2 Middle Aged 2 Retrospective Studies 2 adult 2 aged 2 comparative study 2 cost of illness 2 disease burden 2 factual database 2 health care utilization 2 health insurance 2