Article 5 enzyme linked immunosorbent assay gene expression protein expression Humans 4 Male 4 controlled study 4 genetics 4 human 4 male 4 tumor necrosis factor 4 unclassified drug 4 Female 3 MicroRNAs 3 female 3 human cell 3 interleukin 1beta 3 interleukin 6 3 major clinical study 3 metabolism 3 microRNA 3 pathology 3 real time polymerase chain reaction 3 Aged 2 Apoptosis 2 Case-Control Studies 2 Cell Line 2 Cell Proliferation 2 Gene Expression 2 Pulmonary Disease, Chronic Obstructive 2