Article 3 Biomarkers, Tumor 3 Humans 3 Middle Aged 3 Prognosis 3 adult 3 cancer prognosis 3 chemistry 3 genetics human 3 middle aged mortality 3 prognosis 3 tumor marker Exosomes 2 Female 2 Male 2 RNA, Long Noncoding 2 blood 2 blood sampling 2 controlled study 2 exosome 2 female 2 gene expression 2 long untranslated RNA 2 major clinical study 2 male 2 predictive value 2 sensitivity and specificity 2 ABCA1 gene 1