Article 7 adult 7 human 7 middle aged unclassified drug Humans 6 male 6 Middle Aged 5 female 5 Female 4 Male 4 controlled study 4 Case-Control Studies 3 case control study 3 clinical article 3 genetics 3 human tissue 3 immunohistochemistry 3 major clinical study 3 metabolism 3 pathogenesis 3 Adult 2 Glomerular Filtration Rate 2 MicroRNAs 2 biological marker 2 blood 2 case report 2 cell proliferation 2 complication 2 creatinine 2