mouse nonhuman 54 Animals 52 animal 52 Article 49 controlled study 49 Mice 45 animal experiment 42 human 38 metabolism 36 animal model 33 male 32 animal cell 29 Humans 27 animal tissue 25 female 24 enzyme linked immunosorbent assay 20 genetics 18 unclassified drug 18 drug effect 14 in vitro study 14 in vivo study 14 protein expression 14 Female 13 Male 13 enzyme activity 13 adult 12 human cell 12 Disease Models, Animal 11 chemistry 11