human 5 nonhuman Article 4 animal experiment 3 animal tissue 3 controlled study 3 drug penetration 3 human cell 3 in vitro study 3 male 3 metabolism 3 Animals 2 Drug Carriers 2 Humans 2 Permeability 2 alcohol 2 animal 2 animal model 2 apoptosis 2 chemistry 2 drug carrier 2 drug cytotoxicity 2 drug delivery system 2 drug retention 2 fluorouracil 2 in vivo study 2 microwave radiation 2 mouse 2 nanoencapsulation 2 particle size 2