human 6 tricyclic antidepressant agent Article 5 Humans 5 female 5 male 5 adult 4 aged 4 major clinical study 4 serotonin uptake inhibitor 4 Adult 3 Female 3 Male 3 Middle Aged 3 antidepressant agent 3 cohort analysis 3 depression 3 middle aged 3 serotonin noradrenalin reuptake inhibitor 3 Aged 2 Depressive Disorder, Major 2 United States 2 anticonvulsive agent 2 atypical antipsychotic agent 2 benzodiazepine derivative 2 body mass 2 clinical feature 2 controlled study 2 demography 2 drug dependence 2