Article 6 upregulation controlled study 5 mitogen activated protein kinase 5 signal transduction 5 MAPK signaling 4 down regulation 4 human 4 genetics 3 human cell 3 microarray analysis 3 protein expression 3 protein p53 3 Humans 2 RNA extraction 2 Western blotting 2 adult 2 animal experiment 2 animal model 2 antineoplastic activity 2 apoptosis 2 cell cycle arrest 2 cell proliferation 2 cell viability 2 clinical article 2 drug effect 2 flow cytometry 2 focal adhesion 2 gene expression 2 gene expression profiling 2