RASSF1A Suppression as a Potential Regulator of Mechano-Pathobiology Associated with Mammographic Density in BRCA Mutation Carriers

by Gina Reye, Xuan Huang, Kara L. Britt, Christoph Meinert, Tony Blick, Yannan Xu, Konstantin I. Momot, Thomas Lloyd, Jason J. Northey, Erik W. Thompson, Honor J. Hugo
Published 2021-06-01

Identification of Variants (rs11571707, rs144848, and rs11571769) in the <i>BRCA2</i> Gene Associated with Hereditary Breast Cancer in Indigenous Populations of the Brazilian Amazo...

by Elizabeth Ayres Fragoso Dobbin, Jéssyca Amanda Gomes Medeiros, Marta Solange Camarinha Ramos Costa, Juliana Carla Gomes Rodrigues, João Farias Guerreiro, José Eduardo Kroll, Sandro José de Souza, Paulo Pimentel de Assumpção, Ândrea Ribeiro-dos-Santos, Sidney Emanuel Batista dos Santos, Rommel Mario Rodríguez Burbano, Marianne Rodrigues Fernandes, Ney Pereira Carneiro dos Santos
Published 2021-01-01

The Role of <i>BRCA1/2</i>-Mutated Tumor Microenvironment in Breast Cancer

by Svetlana Miklikova, Lenka Trnkova, Jana Plava, Martin Bohac, Marcela Kuniakova, Marina Cihova
Published 2021-02-01

Front-Line Maintenance Therapy in Advanced Ovarian Cancer—Current Advances and Perspectives

by Thibaut Reverdy, Christophe Sajous, Julien Péron, Olivier Glehen, Naoual Bakrin, Witold Gertych, Jonathan Lopez, Benoit You, Gilles Freyer
Published 2020-08-01

A Recurrent <i>BRCA2</i> Mutation Explains the Majority of Hereditary Breast and Ovarian Cancer Syndrome Cases in Puerto Rico

by Hector J. Diaz-Zabala, Ana P. Ortiz, Lisa Garland, Kristine Jones, Cynthia M. Perez, Edna Mora, Nelly Arroyo, Taras K. Oleksyk, Miguel Echenique, Jaime L. Matta, Michael Dean, Julie Dutil
Published 2018-11-01

<i>Let-7i</i> Reduces Aggressive Phenotype and Induces <i>BRCAness</i> in Ovarian Cancer Cells

by Evgeny Chirshev, Tise Suzuki, Hanmin Wang, Anthony Nguyen, Nozomi Hojo, Linda Sanderman, Saied Mirshahidi, Yevgeniya J. Ioffe, Juli J. Unternaehrer
Published 2021-09-01

Transcriptome Patterns of <i>BRCA1</i>- and <i>BRCA2</i>- Mutated Breast and Ovarian Cancers

by Arsen Arakelyan, Ani Melkonyan, Siras Hakobyan, Uljana Boyarskih, Arman Simonyan, Lilit Nersisyan, Maria Nikoghosyan, Maxim Filipenko, Hans Binder
Published 2021-01-01

Breast Cancer Mortality among Women with a <em>BRCA1</em> or <em>BRCA2</em> Mutation in a Magnetic Resonance Imaging Plus Mammography Screening Program

by Ellen Warner, Siqi Zhu, Donald B. Plewes, Kimberley Hill, Elizabeth A. Ramsay, Petrina A. Causer, Jean Seely, Roberta A. Jong, Pamela Lenkov, Christine Elser, Pavel Crystal, Martin J. Yaffe, Vasily Giannakeas, Ping Sun, Steven A. Narod
Published 2020-11-01

Population Study of Ovarian Cancer Risk Prediction for Targeted Screening and Prevention

by Faiza Gaba, Oleg Blyuss, Xinting Liu, Shivam Goyal, Nishant Lahoti, Dhivya Chandrasekaran, Margarida Kurzer, Jatinderpal Kalsi, Saskia Sanderson, Anne Lanceley, Munaza Ahmed, Lucy Side, Aleksandra Gentry-Maharaj, Yvonne Wallis, Andrew Wallace, Jo Waller, Craig Luccarini, Xin Yang, Joe Dennis, Alison Dunning, Andrew Lee, Antonis C. Antoniou, Rosa Legood, Usha Menon, Ian Jacobs, Ranjit Manchanda
Published 2020-05-01

Hereditary Breast and Ovarian Cancer in Families from Southern Italy (Sicily)—Prevalence and Geographic Distribution of Pathogenic Variants in <i>BRCA1/2</i> Genes

by Lorena Incorvaia, Daniele Fanale, Giuseppe Badalamenti, Marco Bono, Valentina Calò, Daniela Cancelliere, Marta Castiglia, Alessia Fiorino, Alessia Pivetti, Nadia Barraco, Sofia Cutaia, Antonio Russo, Viviana Bazan
Published 2020-05-01

Causes for Frequent Pathogenic <i>BRCA1</i> Variants Include Low Penetrance in Fertile Ages, Recurrent De-Novo Mutations and Genetic Drift

by Pål Møller, Mev Dominguez-Valentin, Einar Andreas Rødland, Eivind Hovig
Published 2019-01-01

A Multi-Center Study of <i>BRCA1</i> and <i>BRCA2</i> Germline Mutations in Mexican-Mestizo Breast Cancer Families Reveals Mutations Unreported in Latin American Population

by Oliver Millan Catalan, Alma D. Campos-Parra, Rafael Vázquez-Romo, David Cantú de León, Nadia Jacobo-Herrera, Fermín Morales-González, César López-Camarillo, Mauricio Rodríguez-Dorantes, Eduardo López-Urrutia, Carlos Pérez-Plasencia
Published 2019-08-01

Targeting DNA Damage Repair Mechanisms in Pancreas Cancer

by Lukas Perkhofer, Talia Golan, Pieter-Jan Cuyle, Tamara Matysiak-Budnik, Jean-Luc Van Laethem, Teresa Macarulla, Estelle Cauchin, Alexander Kleger, Alica K. Beutel, Johann Gout, Albrecht Stenzinger, Eric Van Cutsem, Joaquim Bellmunt, Pascal Hammel, Eileen M. O’Reilly, Thomas Seufferlein
Published 2021-08-01

Breast Cancer Predisposition Genes and Synthetic Lethality

by Hannah E. Neiger, Emily L. Siegler, Yihui Shi
Published 2021-05-01

A Population-Based Analysis of <i>BRCA1</i>/<i>2</i> Genes and Associated Breast and Ovarian Cancer Risk in Korean Patients: A Multicenter Cohort Study

by Kyung-Sun Park, Woochang Lee, Moon-Woo Seong, Sun-Young Kong, Kyung-A Lee, Jung-Sook Ha, Eun-Hae Cho, Sung-Hee Han, Inho Park, Jong-Won Kim
Published 2021-05-01

Clinicopathological Correlates of γδ T Cell Infiltration in Triple-Negative Breast Cancer

by Florence Boissière-Michot, Ghita Chabab, Caroline Mollevi, Séverine Guiu, Evelyne Lopez-Crapez, Jeanne Ramos, Nathalie Bonnefoy, Virginie Lafont, William Jacot
Published 2021-02-01

Five Italian Families with Two Mutations in <i>BRCA</i> Genes

by Maria Teresa Vietri, Gemma Caliendo, Giovanna D’Elia, Marianna Resse, Amelia Casamassimi, Pellegrino Biagio Minucci, Concetta Dello Ioio, Michele Cioffi, Anna Maria Molinari
Published 2020-12-01

Analysis of <i>BRCA1</i> and <i>RAD51C</i> Promoter Methylation in Italian Families at High-Risk of Breast and Ovarian Cancer

by Silvia Tabano, Jacopo Azzollini, Chiara Pesenti, Sara Lovati, Jole Costanza, Laura Fontana, Bernard Peissel, Monica Miozzo, Siranoush Manoukian
Published 2020-04-01

Non-Coding Variants in <i>BRCA1</i> and <i>BRCA2</i> Genes: Potential Impact on Breast and Ovarian Cancer Predisposition

by Elizabeth Santana dos Santos, François Lallemand, Leslie Burke, Dominique Stoppa-Lyonnet, Melissa Brown, Sandrine M. Caputo, Etienne Rouleau
Published 2018-11-01

Neoadjuvant Chemotherapy of Triple-Negative Breast Cancer: Evaluation of Early Clinical Response, Pathological Complete Response Rates, and Addition of Platinum Salts Benefit Based...

by Milos Holanek, Iveta Selingerova, Ondrej Bilek, Tomas Kazda, Pavel Fabian, Lenka Foretova, Maria Zvarikova, Radka Obermannova, Ivana Kolouskova, Oldrich Coufal, Katarina Petrakova, Marek Svoboda, Alexandr Poprach
Published 2021-03-01