human 45 protein p53 44 Humans 35 Article 30 genetics 30 Tumor Suppressor Protein p53 22 metabolism 21 p53 20 pathology 19 controlled study 18 female 16 gene expression 16 human cell 14 male 14 TP53 13 protein expression 13 Female 12 apoptosis 12 gene mutation 12 nonhuman 12 unclassified drug 12 upregulation 12 adult 11 human tissue 11 signal transduction 11 Apoptosis 10 TP53 protein, human 10 immunohistochemistry 10 Animals 9 animal 9