Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity

by Frederick M. Tomlin, Ulla I. M. Gerling-Driessen, Yi-Chang Liu, Ryan A. Flynn, Janakiram R. Vangala, Christian S. Lentz, Sandra Clauder-Muenster, Petra Jakob, William F. Mueller, Diana Ordoñez-Rueda, Malte Paulsen, Naoko Matsui, Deirdre Foley, Agnes Rafalko, Tadashi Suzuki, Matthew Bogyo, Lars M. Steinmetz, Senthil K. Radhakrishnan, Carolyn R. Bertozzi
Published 2017-10-01

Immunity to α‑Gal: Toward a Single-Antigen Pan-Vaccine To Control Major Infectious Diseases

by Alejandro Cabezas-Cruz, José de la Fuente
Published 2017-11-01

The Development of Global Science

by Kyle E. Cordova, Hiroyasu Furukawa, Omar M. Yaghi
Published 2015-03-01

Reversible Self-Assembled Monolayers (rSAMs): Adaptable Surfaces for Enhanced Multivalent Interactions and Ultrasensitive Virus Detection

by Sing Yee Yeung, Annabell Mucha, Ravindra Deshmukh, Malak Boutrus, Thomas Arnebrant, Börje Sellergren
Published 2017-11-01

Mimicking Melanosomes: Polydopamine Nanoparticles as Artificial Microparasols

by Yuran Huang, Yiwen Li, Ziying Hu, Xiujun Yue, Maria T. Proetto, Ying Jones, Nathan C. Gianneschi
Published 2017-05-01

Catalytic Oxidation of Methane into Methanol over Copper-Exchanged Zeolites with Oxygen at Low Temperature

by Karthik Narsimhan, Kenta Iyoki, Kimberly Dinh, Yuriy Román-Leshkov
Published 2016-06-01

Remote Meta-C–H Activation Using a Pyridine-Based Template: Achieving Site-Selectivity via the Recognition of Distance and Geometry

by Ling Chu, Ming Shang, Keita Tanaka, Qinghao Chen, Natalya Pissarnitski, Eric Streckfuss, Jin-Quan Yu
Published 2015-10-01

The Role of Surface-Bound Dihydropyridine Analogues in Pyridine-Catalyzed CO2 Reduction over Semiconductor Photoelectrodes

by Thomas P. Senftle, Martina Lessio, Emily A. Carter
Published 2017-08-01

In Situ High Temperature Synthesis of Single-Component Metallic Nanoparticles

by Yonggang Yao, Fengjuan Chen, Anmin Nie, Steven D. Lacey, Rohit Jiji Jacob, Shaomao Xu, Zhennan Huang, Kun Fu, Jiaqi Dai, Lourdes Salamanca-Riba, Michael R. Zachariah, Reza Shahbazian-Yassar, Liangbing Hu
Published 2017-04-01

Chemical Synthesis of (+)-Ryanodine and (+)-20-Deoxyspiganthine

by Chen Xu, Arthur Han, Scott C. Virgil, Sarah E. Reisman
Published 2017-03-01

Novel Solutions for Vaccines and Diagnostics To Combat Brucellosis

by Satadru Sekhar Mandal, Lucy Duncombe, N. Vijaya Ganesh, Susmita Sarkar, Laurence Howells, Philip J. Hogarth, David R. Bundle, John McGiven
Published 2017-03-01

Low Data Drug Discovery with One-Shot Learning

by Han Altae-Tran, Bharath Ramsundar, Aneesh S. Pappu, Vijay Pande
Published 2017-04-01

Thirsty California Turns to Sea and Sewer

by Deirdre Lockwood
Published 2015-06-01

A Conversation with Henry Snaith

by Mark Peplow
Published 2015-07-01

Absence of Selection for Quantum Coherence in the Fenna–Matthews–Olson Complex: A Combined Evolutionary and Excitonic Study

by Stéphanie Valleau, Romain A. Studer, Florian Häse, Christoph Kreisbeck, Rafael G. Saer, Robert E. Blankenship, Eugene I. Shakhnovich, Alán Aspuru-Guzik
Published 2017-08-01

The Art of the Chemical Bond

by Stephen K. Ritter
Published 2016-11-01

Fitting Proteins into Metal Organic Frameworks

by Daishi Fujita, Makoto Fujita
Published 2015-09-01

Cavitation-Induced Synthesis of Biogenic Molecules on Primordial Earth

by Natan-Haim Kalson, David Furman, Yehuda Zeiri
Published 2017-09-01

(Near-Infra) Red Means STOP: Shutting Down Cancer with NIR Light

by Evan W. Miller
Published 2017-03-01

Ultrahigh Surface Area Three-Dimensional Porous Graphitic Carbon from Conjugated Polymeric Molecular Framework

by John W. F. To, Zheng Chen, Hongbin Yao, Jiajun He, Kwanpyo Kim, Ho-Hsiu Chou, Lijia Pan, Jennifer Wilcox, Yi Cui, Zhenan Bao
Published 2015-05-01