The Anti-ADAMTS-5 Nanobody^® M6495 Protects Cartilage Degradation Ex Vivo

by Anne Sofie Siebuhr, Daniela Werkmann, Anne-C. Bay-Jensen, Christian S. Thudium, Morten Asser Karsdal, Benedikte Serruys, Christoph Ladel, Martin Michaelis, Sven Lindemann
Published 2020-08-01

Does butein affect adipogenesis?

by Bianca Hemmeryckx, Christine Vranckx, Dries Bauters, H. Roger Lijnen, Ilse Scroyen
Published 2019-01-01

Genetic variation of aggrecanase-2 (ADAMTS5) in susceptibility to osteoarthritis

by Xindie Zhou, Lifeng Jiang, Yi Zhang, Junjie Zhang, Dong Zhou, Lidong Wu, Yong Huang, Nanwei Xu
Published 2019-01-01

Development of a highly sensitive chemiluminescence immunoassay for quantification of aggrecanase-generated ARGS aggrecan fragments in serum

by Yi He, Kamilla E. Jensen, Anne Sofie Siebuhr, Morten A. Karsdal, Jonathan Larkin, Anne C. Bay-Jensen
Published 2021-06-01

Recombinant TSR1 of ADAMTS5 Suppresses Melanoma Growth in Mice via an Anti-angiogenic Mechanism

by Bhuvanasundar Renganathan, Vinoth Durairaj, Dogan Can Kirman, Paa Kow A. Esubonteng, Swee Kim Ang, Ruowen Ge
Published 2018-06-01

Hemoglobin stimulates the expression of ADAMTS-5 and ADAMTS-9 by synovial cells: a possible cause of articular cartilage damage after intra-articular hemorrhage

by Takuya Tajima, Tomohisa Sekimoto, Nami Yamaguchi, Noboru Taniguchi, Syuji Kurogi, Masugi Maruyama, Etsuo Chosa
Published 2017-11-01

Activation of β-catenin signalling leads to temporomandibular joint defects

by M Wang, S Li, W Xie, J Shen, H-J Im, JD Holz, M Wang, TGH Diekwisch, D Chen
Published 2014-10-01

Matrilin-2 Is Proteolytically Cleaved by ADAMTS-4 and ADAMTS-5

by Zhengke Wang, Junming Luo, Satori Iwamoto, Qian Chen
Published 2014-06-01

Loss of ADAMTS5 enhances brown adipose tissue mass and promotes browning of white adipose tissue via CREB signaling

by Dries Bauters, Mathias Cobbaut, Lotte Geys, Johan Van Lint, Bianca Hemmeryckx, H. Roger Lijnen
Published 2017-07-01

ADAMTS-5: The story so far

by A J Fosang, F M Rogerson, C J East, H Stanton
Published 2008-02-01

Extracellular vesicles derived from LPS-preconditioned human synovial mesenchymal stem cells inhibit extracellular matrix degradation and prevent osteoarthritis of the knee in a mo...

by Ao Duan, Kai Shen, Beichen Li, Cong Li, Hao Zhou, Renyi Kong, Yuqi Shao, Jian Qin, Tangbo Yuan, Juan Ji, Wei Guo, Xipeng Wang, Tengfei Xue, Lei Li, Xinxin Huang, Yuqin Sun, Zhenyu Cai, Wei Liu, Feng Liu
Published 2021-07-01

LncRNA MIR22HG promotes osteoarthritis progression via regulating miR-9-3p/ADAMTS5 pathway

by Hui Long, Qin Li, Zhenping Xiao, Bo Yang
Published 2021-01-01

Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes

by Chang Tu, Xiaojian Huang, Yifan Xiao, Mingyu Song, Yongzhuang Ma, Jiyuan Yan, Hongbo You, Hua Wu
Published 2019-01-01

ADAMTS5 in Osteoarthritis: Biological Functions, Regulatory Network, and Potential Targeting Therapies

by Lejian Jiang, Lejian Jiang, Jiachen Lin, Jiachen Lin, Jiachen Lin, Sen Zhao, Sen Zhao, Sen Zhao, Jiaqian Wu, Yongming Jin, Li Yu, Nan Wu, Nan Wu, Nan Wu, Zhihong Wu, Zhihong Wu, Zhihong Wu, Yue Wang, Yue Wang, Mao Lin, Mao Lin, Mao Lin, Mao Lin
Published 2021-08-01

Dualité d'action de la galectine-3 dans la pathophysiologie de l'arthrose

by Janelle-Montcalm, Audrée
Published 2016

ADAMTS-5 Decreases in Aortas and Plasma From Aortic Dissection Patients and Alleviates Angiotensin II-Induced Smooth Muscle-Cell Apoptosis

by Tao Zeng, Jianting Gan, Yu Liu, Lei Shi, Zhengde Lu, Yan Xue, Rixin Xiong, Ling Liu, Zicong Yang, Yingzhong Lin, Jun Yuan
Published 2020-08-01

HOXC13-AS Induced Extracellular Matrix Loss via Targeting miR-497-5p/ADAMTS5 in Intervertebral Disc

by Wanli Jing, Wei Liu
Published 2021-07-01

Circ-SPG11 knockdown hampers IL-1β-induced osteoarthritis progression via targeting miR-337-3p/ADAMTS5

by Yongqiang Liu, Qian Li, Zhida Gao, Fang Lei, Xuefeng Gao
Published 2021-06-01

Treatment of Dystrophic <i>mdx </i>Mice with an ADAMTS-5 Specific Monoclonal Antibody Increases the Ex Vivo Strength of Isolated Fast Twitch Hindlimb Muscles

by Alex B. Addinsall, Leonard G. Forgan, Natasha L. McRae, Rhys W. Kelly, Penny L. McDonald, Bryony McNeill, Daniel R. McCulloch, Nicole Stupka
Published 2020-03-01

miR-21-5p protects IL-1β-induced human chondrocytes from degradation

by Hai Zhu, Xin Yan, Meng Zhang, Feng Ji, Shouguo Wang
Published 2019-05-01