Metformin + Sodium-glucose Co-transporter-2 Inhibitor: Salutogenic Lifestyle Mimetics in a Tablet?

by Sanjay Kalra, Jubbin Jacob, Manash P Baruah
Published 2018-01-01

Pyrvinium Treatment Confers Hepatic Metabolic Benefits via β-Catenin Downregulation and AMPK Activation

by Shiwei Zhou, Obinna N. Obianom, Jiangsheng Huang, Dong Guo, Hong Yang, Qing Li, Yan Shu
Published 2021-03-01

Long Feeding High-Fat Diet Induces Hypothalamic Oxidative Stress and Inflammation, and Prolonged Hypothalamic AMPK Activation in Rat Animal Model

by Gina Cavaliere, Emanuela Viggiano, Emanuela Viggiano, Giovanna Trinchese, Chiara De Filippo, Antonietta Messina, Vincenzo Monda, Anna Valenzano, Raffaele I. Cincione, Christian Zammit, Fabiano Cimmino, Angela Catapano, Francesco Sessa, Giovanni Messina, Marcellino Monda, Marianna Crispino, Maria Pina Mollica
Published 2018-07-01

Metformin: A Prospective Alternative for the Treatment of Chronic Pain

by Guadalupe Del Carmen Baeza-Flores, Crystell Guadalupe Guzmán-Priego, Leonor Ivonne Parra-Flores, Janet Murbartián, Jorge Elías Torres-López, Jorge Elías Torres-López, Vinicio Granados-Soto
Published 2020-09-01

Metformin-Encapsulated Liposome Delivery System: An Effective Treatment Approach against Breast Cancer

by Snehal K. Shukla, Nishant S. Kulkarni, Amanda Chan, Vineela Parvathaneni, Pamela Farrales, Aaron Muth, Vivek Gupta
Published 2019-10-01

Alpha-Mangostin Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice Partly Through Activating Adenosine 5′-Monophosphate-Activated Protein Kinase

by Ren-shi Li, Ren-shi Li, Gong-hao Xu, Juan Cao, Bei Liu, Hai-feng Xie, Yuji Ishii, Chao-feng Zhang, Chao-feng Zhang
Published 2019-11-01

Galactomannan Pentasaccharide Produced from Copra Meal Enhances Tight Junction Integration of Epithelial Tissue through Activation of AMPK

by Chatchai Nopvichai, Pawin Pongkorpsakol, Preedajit Wongkrasant, Karan Wangpaiboon, Thanapon Charoenwongpaiboon, Kazuo Ito, Chatchai Muanprasat, Rath Pichyangkura
Published 2019-10-01

Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway

by Yasuhiro Nishida, Allah Nawaz, Tomonobu Kado, Akiko Takikawa, Yoshiko Igarashi, Yasuhiro Onogi, Tsutomu Wada, Toshiyasu Sasaoka, Seiji Yamamoto, Masakiyo Sasahara, Johji Imura, Kumpei Tokuyama, Isao Usui, Takashi Nakagawa, Shiho Fujisaka, Yagi Kunimasa, Kazuyuki Tobe
Published 2020-02-01

A Facile Synthesis of 5'-Fluoro-5'-deoxyacadesine (5'-F-AICAR): A Novel Non-phosphorylable AICAR Analogue

by Luciano Mayol, Vincenzo Piccialli, Daniele D'Alonzo, Jussara Amato, Nicola Borbone, Giorgia Oliviero, Stefano D'Errico, Gennaro Piccialli
Published 2012-11-01

The isomiR-140-3p-regulated mevalonic acid pathway as a potential target for prevention of triple negative breast cancer

by Anjana Bhardwaj, Harpreet Singh, Celestine Marie Trinidad, Constance T. Albarracin, Kelly K. Hunt, Isabelle Bedrosian
Published 2018-12-01

Synthesis of New Acadesine (AICA-riboside) Analogues Having Acyclic d-Ribityl or 4-Hydroxybutyl Chains in Place of the Ribose

by Gennaro Piccialli, Luciano Mayol, Michela Varra, Giorgia Oliviero, Nicola Borbone, Jussara Amato, Vincenzo Piccialli, Stefano D'Errico
Published 2013-08-01

Rutin Increases Muscle Mitochondrial Biogenesis with AMPK Activation in High-Fat Diet-Induced Obese Rats

by Sangjin Seo, Mak-Soon Lee, Eugene Chang, Yoonjin Shin, Soojung Oh, In-Hwan Kim, Yangha Kim
Published 2015-09-01

Maternal High Fat Diet Programs Male Mice Offspring Hyperphagia and Obesity: Mechanism of Increased Appetite Neurons via Altered Neurogenic Factors and Nutrient Sensor AMPK

by Mina Desai, Monica G. Ferrini, Guang Han, Kavita Narwani, Michael G. Ross
Published 2020-10-01

The Role of AMP-Activated Protein Kinase as a Potential Target of Treatment of Hepatocellular Carcinoma

by Xue Jiang, Hor-Yue Tan, Shanshan Teng, Yau-Tuen Chan, Di Wang, Ning Wang
Published 2019-05-01

Activation of the AMP-related kinase (AMPK) induces renal vasodilatation and downregulates Nox-derived reactive oxygen species (ROS) generation

by Claudia Rodríguez, Cristina Contreras, Javier Sáenz-Medina, Mercedes Muñoz, César Corbacho, Joaquín Carballido, Albino García-Sacristán, Medardo Hernandez, Miguel López, Luis Rivera, Dolores Prieto
Published 2020-07-01

Antidiabetic effect of free amino acids supplementation in human visceral adipocytes through adiponectin-dependent mechanism

by Vidhya Srinivasan, Selvi Radhakrishnan, Narayanasamy Angayarkanni, K N Sulochana
Published 2019-01-01

Metformin does not compromise energy status in human skeletal muscle at rest or during acute exercise: A randomised, crossover trial

by Jonas M. Kristensen, Christian Lillelund, Rasmus Kjøbsted, Jesper B. Birk, Nicoline R. Andersen, Lars Nybo, Karin Mellberg, Anudharan Balendran, Erik A. Richter, Jørgen F. P. Wojtaszewski
Published 2019-12-01

Regulation of AMP-activated protein kinase by natural and synthetic activators

by David Grahame Hardie
Published 2016-01-01

AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development

by Nadia Boudaba, Allison Marion, Camille Huet, Rémi Pierre, Benoit Viollet, Marc Foretz
Published 2018-02-01

AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells

by Séverine Olivier, Jocelyne Leclerc, Adrien Grenier, Marc Foretz, Jérôme Tamburini, Benoit Viollet
Published 2019-10-01